Evidence map›Paper›PMID 37186512›Full record

ArticleAdvanced healthcare materials2023

Versatile Microfluidics for Biofabrication Platforms Enabled by an Agile and Inexpensive Fabrication Pipeline.

Amirpasha Moetazedian, Alessia Candeo, Siyun Liu, Arran Hughes, Vahid Nasrollahi, Mozafar Saadat, Andrea Bassi, Liam M Grover, Liam R Cox, Gowsihan Poologasundarampillai

Open access · hybridAbstract read
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Amirpasha MoetazedianSchool of Dentistry, Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, B5 7EG, UK.ORCID 0000-0003-1457-2854
Alessia CandeoDipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy.
Siyun LiuSchool of Dentistry, Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, B5 7EG, UK.
Arran HughesDepartment of Mechanical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Vahid NasrollahiDepartment of Mechanical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Mozafar SaadatDepartment of Mechanical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Andrea BassiDipartimento di Fisica, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milano, 20133, Italy.
Liam M GroverSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Liam R CoxSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.
Gowsihan PoologasundarampillaiSchool of Dentistry, Institute of Clinical Sciences, University of Birmingham, Edgbaston, Birmingham, B5 7EG, UK.
University of Birmingham · GBPolitecnico di Milano · ITEngineering and Physical Sciences Research Council · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microfluidics have transformed diagnosis and screening in regenerative medicine. Recently, they are showing much promise in biofabrication. However, their adoption is inhibited by costly and drawn-out lithographic processes thus limiting progress. Here, multi-material fibers with complex core-shell geometries with sizes matching those of human arteries and arterioles are fabricated employing versatile microfluidic devices produced using an agile and inexpensive manufacturing pipeline. The pipeline consists of material extrusion additive manufacturing with an innovative continuously varied extrusion (CONVEX) approach to produce microfluidics with complex seamless geometries including, novel variable-width zigzag (V-zigzag) mixers with channel widths ranging from 100-400 µm and hydrodynamic flow-focusing components. The microfluidic systems facilitated rapid mixing of fluids by decelerating the fluids at specific zones to allow for increased diffusion across the interfaces. Better mixing even at high flow rates (100-1000 µL min

Indexed as

Lab-On-A-Chip DevicesMicrofluidicsHumansHydrodynamicsPrinting, Three-DimensionalRegenerative Medicineadditive manufacturingbiofabricationfluid dynamicsfluidicshelical fibers

Identifiers

PMID37186512
PMCPMC11468497
OpenAlexW4367052590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.