ArticleSchizophrenia bulletin2023
Development and Validation of the Negative Symptom Inventory-Psychosis Risk.
Article in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 25 citations in OpenAlex.
- The effect of monetary versus point-based rewards on effort-cost decision making in individuals at clinical high risk for psychosis.Schizophrenia research · 2026Trial
- Premorbid adjustment problems, negative symptoms, and cognitive impairment in a large international sample at clinical high risk for psychosis: Findings from the Accelerating Medicines Partnership-Schizophrenia.Schizophrenia bulletin · 2026Article
- Value representation in youth psychopathology: evidence of a transdiagnostic risk mechanism for psychosis.Translational psychiatry · 2026Article
- Computational phenotypes underlying effort-based decision-making and negative symptoms in a transdiagnostic severe mental illness sample.Molecular psychiatry · 2026Article
- Exploring the Pathways Between Early Auditory Processing, Processing Speed, Social Cognition, and Negative Symptoms on Social Functioning in Individuals at Clinical High Risk for Psychosis: A Structural Equation Modeling Approach.Biological psychiatry · 2026Article
- Temporal Relationship Between Momentary Negative Affect Intensity and Momentary Attenuated Delusions in Individuals at Clinical High-risk for Psychosis.Schizophrenia bulletin · 2026Article
- Impairments in biological motion perception reflect affective disturbance in individuals at clinical high-risk for psychosis.Schizophrenia research. Cognition · 2026Article
- Subjective Perceptions of Digital Phenotyping Measures of Negative Symptoms Among Individuals At Clinical High Risk for Psychosis and Their Relatives.Schizophrenia bulletin open · 2026Article
- Digital Phenotyping Measurement of Smartphone Social Behavior is Associated with Illness Progression Risk Scores in Young People at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2025Article
- The Negative Symptom Inventory-Psychosis Risk (NSI-PR): Psychometric Validation of the Final 11-Item Version.Schizophrenia bulletin · 2025Article
- Subjective emotional experiences in clinical high-risk youth: Insights from a dyadic interaction paradigm.Schizophrenia research · 2025Article
- Digital phenotyping evidence for the reduced positivity offset as a mechanism underlying anhedonia among individuals at clinical high-risk for psychosis.Schizophrenia research · 2025Article
- Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program.Schizophrenia (Heidelberg, Germany) · 2025Article
- Probabalistic reinforcement learning impairments predict negative symptom severity and risk for conversion in youth at clinical high-risk for psychosis.Psychological medicine · 2025Article
- Deconstructing the nature of emotion regulation impairments at the identification, selection, and implementation stages in individuals at clinical high-risk for psychosis.Psychological medicine · 2025Article
- A generalized reward processing deficit pathway to negative symptoms across diagnostic boundaries.Psychological medicine · 2025Article
- Baseline Social Functioning Is Associated with Increased Likelihood of Remission from a Clinical High Risk for Psychosis Syndrome.Schizophrenia bulletin open · 2025Article
- Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program.Schizophrenia bulletin open · 2025Article
- The Complex Latent Structure of Attenuated Psychotic Symptoms: Hierarchical and Bifactor Models of SIPS Symptoms Replicated in Two Large Samples at Clinical High Risk for Psychosis.Schizophrenia bulletin · 2024Article
- Persistent negative symptoms in young people at clinical high risk of psychosis treated with an Italian early intervention program: a longitudinal study.European archives of psychiatry and clinical neuroscience · 2024Article
Corrections and comments
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Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
background and hypothesesEarly identification and prevention of psychosis is limited by the availability of tools designed to assess negative symptoms in those at clinical high-risk for psychosis (CHR). To address this critical need, a multi-site study was established to develop and validate a clinical rating scale designed specifically for individuals at CHR: The Negative Symptom Inventory-Psychosis Risk (NSI-PR). STUDY
designThe measure was developed according to guidelines recommended by the NIMH Consensus Conference on Negative Symptoms using a transparent, iterative, and data-driven process. A 16-item version of the NSI-PR was designed to have an overly inclusive set of items and lengthier interview to support the ultimate intention of creating a new briefer measure. Psychometric properties of the 16-item NSI-PR were evaluated in a sample of 218 CHR participants. STUDY
resultsItem-level analyses indicated that men had higher scores than women. Reliability analyses supported internal consistency, inter-rater agreement, and temporal stability. Associations with measures of negative symptoms and functioning supported convergent validity. Small correlations with positive, disorganized, and general symptoms supported discriminant validity. Structural analyses indicated a 5-factor structure (anhedonia, avolition, asociality, alogia, and blunted affect). Item response theory identified items for removal and indicated that the anchor range could be reduced. Factor loadings, item-level correlations, item-total correlations, and skew further supported removal of certain items.
conclusionsThese findings support the psychometric properties of the NSI-PR and guided the creation of a new 11-item NSI-PR that will be validated in the next phase of this multi-site scale development project.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.