Evidence map›Paper›PMID 37185571›Full record

ArticleScientific reports2023

Marital status and long-term cardiovascular risk in general population (Gubbio, Italy).

Xavier Humbert, Andry Rabiaza, Sophie Fedrizzi, Joachim Alexandre, Alessandro Menotti, Emmanuel Touzé, Martino Laurenzi, Oscar Terradura-Vagnarelli, Paolo E Puddu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Observational
  7. Marital Failure and Subsequent Heart Failure: A Prospective Study.Journal of the American Heart Association · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Xavier HumbertDépartement de medecine generale, Normandie Université, UNICAEN, 14000, Caen, France. xavier.humbert@unicaen.fr.
Andry RabiazaDépartement de medecine generale, Normandie Université, UNICAEN, 14000, Caen, France.
Sophie FedrizziEA 4650, Signalisation, électrophysiologie et imagerie des lesions d'ischémie reperfusion myocardique, UNICAEN, 14000, Caen, France.
Joachim AlexandreINSERM U1086 ANTICIPE, Normandie Université, UNICAEN, 14000, Caen, France.
Alessandro MenottiAssociation for Cardiac Research, 00198, Rome, Italy.
Emmanuel TouzéService de Neurologie, Normandie Université, UNICAEN, CHU Caen Normandie, 14000, Caen, France.
Martino LaurenziCentro Studi Epidemiologici di Gubbio (CeSEG), 06024, Gubbio, Perugia, Italy.
Oscar Terradura-VagnarelliCentro Studi Epidemiologici di Gubbio (CeSEG), 06024, Gubbio, Perugia, Italy.
Paolo E PudduEA 4650, Signalisation, électrophysiologie et imagerie des lesions d'ischémie reperfusion myocardique, UNICAEN, 14000, Caen, France.
Italian Association for Cancer Research · ITNormandie Université · FRCentre Hospitalier Universitaire de Caen · FRInserm · FRUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate whether marital status is associated to long-term major fatal and non-fatal cardiovascular events in men and women from the Gubbio Population Study. The incidence of cardiovascular disease (CVD), including stroke and coronary heart disease (CHD) and CVD death together with all-cause mortality were analyzed. The analysis included 2832 persons (44% men, 54 ± 11 years old). Marital status was defined at entry as married (married or living conjugally) versus unmarried subjects (widowed, separated, divorced or single). Married and unmarried subjects did not differ concerning socio-demographic, anthropometric and biological variables at baseline. Over 191 months median follow-up, the incidence of CHD was lower among married versus unmarried women [HR: 0.63 (95% CI 0.41-0.96)] only; the same was true for CHD mortality [HR: 0.43 (95% CI 0.22-0.84)] and all-cause mortality [HR: 0.75 (95% CI 0.59-0.96)] independently of traditional risk factors (age, SBP, total and HDL cholesterol, cigarette smoke and BMI). In men, marital status was not associated to any of the investigated outcomes. In primary care, marital status should be investigated as it can be associated with long-term CHD and all-cause incidence and mortality risks among women.

Indexed as

Cardiovascular DiseasesCoronary DiseaseAdultAgedFemaleHeart Disease Risk FactorsHumansItalyMaleMarital StatusMiddle AgedRisk Factors

Identifiers

PMID37185571
PMCPMC10130019
OpenAlexW4366987078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.