Evidence map›Paper›PMID 37185544›Full record

ReviewBiosensors2023

Applications of Transistor-Based Biochemical Sensors.

Qiya Gao, Jie Fu, Shuang Li, Dong Ming

Abstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiya GaoAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.
Jie FuAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.
Shuang LiAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.ORCID 0000-0002-3483-5087
Dong MingAcademy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China.

Funding

HongKong Scholars Program XJ2021034National Key Research and Development Program of China 2022YFF1202704National Natural Science Foundation of China 82001922
6 · The paper itself

Abstract

Transistor-based biochemical sensors feature easy integration with electronic circuits and non-invasive real-time detection. They have been widely used in intelligent wearable devices, electronic skins, and biological analyses and have shown broad application prospects in intelligent medical detection. Field-effect transistor (FET) sensors have high sensitivity, reasonable specificity, rapid response, and portability and provide unique signal amplification during biochemical detection. Organic field-effect transistor (OFET) sensors are lightweight, flexible, foldable, and biocompatible with wearable devices. Organic electrochemical transistor (OECT) sensors convert biological signals in body fluids into electrical signals for artificial intelligence analysis. In addition to biochemical markers in body fluids, electrophysiology indicators such as electrocardiogram (ECG) signals and body temperature can also cause changes in the current or voltage of transistor-based biochemical sensors. When modified with sensitive substances, sensors can detect specific analytes, improve sensitivity, broaden the detection range, and reduce the limit of detection (LoD). In this review, we introduce three kinds of transistor-based biochemical sensors: FET, OFET, and OECT. We also discuss the fabrication processes for transistor sources, drains, and gates. Furthermore, we demonstrated three sensor types for body fluid biomarkers, electrophysiology signals, and development trends. Transistor-based biochemical sensors exhibit excellent potential in multi-mode intelligent analysis and are good candidates for the next generation of intelligent point-of-care testing (iPOCT).

Indexed as

Biosensing TechniquesBody FluidsWearable Electronic DevicesArtificial IntelligenceBiomarkersTransistors, ElectronicBiomarkersbiochemical sensorfield-effect transistor (FET)intelligent point-of-care testing (iPOCT)organic electrochemical transistor (OECT)organic field-effect transistor (OFET)

Identifiers

PMID37185544
PMCPMC10136501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.