Evidence map›Paper›PMID 37185514›Full record

ReviewBiosensors2023

Optical Detection of Cancer Cells Using Lab-on-a-Chip.

Luis Abraham García-Hernández, Eduardo Martínez-Martínez, Denni Pazos-Solís, Javier Aguado-Preciado, Ateet Dutt, Abraham Ulises Chávez-Ramírez, Brian Korgel, Ashutosh Sharma, Goldie Oza

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Luis Abraham García-HernándezCentro de Investigación y Desarrollo Tecnológico en Electroquímica, Parque Tecnológico Querétaro, Pedro Escobedo, Querétaro C.P. 76703, Mexico.ORCID 0000-0002-9092-5597
Eduardo Martínez-MartínezInstituto Nacional de Medicina Genómica, Mexico City C.P. 14610, Mexico.ORCID 0000-0002-9020-559X
Denni Pazos-SolísTecnologico de Monterrey, School of Engineering and Sciences, Centre of Bioengineering, Campus Queretaro, Querétaro C.P. 76130, Mexico.
Javier Aguado-PreciadoTecnologico de Monterrey, School of Engineering and Sciences, Centre of Bioengineering, Campus Queretaro, Querétaro C.P. 76130, Mexico.
Ateet DuttInstituto de Investigaciones en Materiales, Circuito Exterior S/N Ciudad Universitaria, Mexico City C.P. 04510, Mexico.ORCID 0000-0002-8106-3120
Abraham Ulises Chávez-RamírezCentro de Investigación y Desarrollo Tecnológico en Electroquímica, Parque Tecnológico Querétaro, Pedro Escobedo, Querétaro C.P. 76703, Mexico.
Brian KorgelMcKetta Department of Chemical Engineering and Texas Materials Institute, The University of Texas at Austin, Austin, TX 78712-1062, USA.
Ashutosh SharmaTecnologico de Monterrey, School of Engineering and Sciences, Centre of Bioengineering, Campus Queretaro, Querétaro C.P. 76130, Mexico.ORCID 0000-0002-9000-1378
Goldie OzaCentro de Investigación y Desarrollo Tecnológico en Electroquímica, Parque Tecnológico Querétaro, Pedro Escobedo, Querétaro C.P. 76703, Mexico.ORCID 0000-0003-1051-0795
Center of Research and Technologic Development in Electrochemistry · MXInstituto Tecnológico de Querétaro · MXNational Institute of Genomic Medicine · MXThe University of Texas at Austin · US

Funding

CIDETEQ 0028Conacyt (Ciencias de Froneras) 2096211
6 · The paper itself

Abstract

The global need for accurate and efficient cancer cell detection in biomedicine and clinical diagnosis has driven extensive research and technological development in the field. Precision, high-throughput, non-invasive separation, detection, and classification of individual cells are critical requirements for successful technology. Lab-on-a-chip devices offer enormous potential for solving biological and medical problems and have become a priority research area for microanalysis and manipulating cells. This paper reviews recent developments in the detection of cancer cells using the microfluidics-based lab-on-a-chip method, focusing on describing and explaining techniques that use optical phenomena and a plethora of probes for sensing, amplification, and immobilization. The paper describes how optics are applied in each experimental method, highlighting their advantages and disadvantages. The discussion includes a summary of current challenges and prospects for cancer diagnosis.

Indexed as

Biosensing TechniquesNeoplasmsLab-On-A-Chip DevicesOptical PhenomenaOptics and PhotonicsSpectrum Analysis, Ramancancerchemiluminescencefluorescencelab-on-a-chipoptical detectionsurface-enhanced Raman scattering SERSsurface plasmon resonance SPR

Identifiers

PMID37185514
PMCPMC10136345
OpenAlexW4361267411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.