Evidence map›Paper›PMID 37185178›Full record

ArticleBMJ open2023

Estimating the cost-effectiveness and return on investment of the Victorian Cardiac Outcomes Registry in Australia: a minimum threshold analysis.

Peter Lee, Angela L Brennan, Dion Stub, Diem T Dinh, Jeffrey Lefkovits, Christopher M Reid, Ella Zomer, Danny Liew

Abstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter LeeSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia peter.lee@deakin.edu.au.ORCID 0000-0001-7059-1959
Angela L BrennanSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Dion StubSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Diem T DinhSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Jeffrey LefkovitsSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Christopher M ReidSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Ella ZomerSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.
Danny LiewSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe sought to establish the minimum level of clinical benefit attributable to the Victorian Cardiac Outcomes Registry (VCOR) for the registry to be cost-effective.

designA modelled cost-effectiveness study of VCOR was conducted from the Australian healthcare system and societal perspectives.

settingObserved deaths and costs attributed to coronary heart disease (CHD) over a 5-year period (2014-2018) were compared with deaths and costs arising from a hypothetical situation which assumed that VCOR did not exist. Data from the Australian Bureau of Statistics and published sources were used to construct a decision analytic life table model to simulate the follow-up of Victorians aged ≥25 years for 5 years, or until death. The assumed contribution of VCOR to the proportional change in CHD mortality trend observed over the study period was varied to quantify the minimum level of clinical benefits required for the registry to be cost-effective. The marginal costs of VCOR operation and years of life saved (YoLS) were estimated. PRIMARY OUTCOME MEASURES: The return on investment (ROI) ratio and the incremental cost-effectiveness ratio (ICER).

resultsThe minimum proportional change in CHD mortality attributed to VCOR required for the registry to be considered cost-effective was 0.125%. Assuming this clinical benefit, a net return of $A4.30 for every dollar invested in VCOR was estimated (ROI ratio over 5 years: 4.3 (95% CI 3.6 to 5.0)). The ICER estimated for VCOR was $A49 616 (95% CI $A42 228 to $A59 608) per YoLS. Sensitivity analyses found that the model was sensitive to the time horizon assumed and the extent of registry contribution to CHD mortality trends.

conclusionsVCOR is likely cost-effective and represents a sound investment for the Victorian healthcare system. Our evaluation highlights the value of clinical quality registries in Australia.

Indexed as

Coronary DiseaseAustraliaCost-Benefit AnalysisDelivery of Health CareHumansRegistriescardiologycoronary interventionhealth economicsmyocardial infarctionpublic health

Identifiers

PMID37185178
PMCPMC10151970

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.