Evidence map›Paper›PMID 37184385›Full record

ArticleApplied and environmental microbiology2023

Regulation and Functionality of a Holin/Endolysin Pair Involved in Killing of Galleria mellonella and Caenorhabditis elegans by Yersinia enterocolitica.

Philipp-Albert Sänger, Mandy Knüpfer, Marcel Kegel, Britta Spanier, Elisabeth M Liebler-Tenorio, Thilo M Fuchs

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
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  4. Comparative genomics-based insights intoApplied and environmental microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Philipp-Albert SängerFriedrich-Loeffler-Institut, Institute of Molecular Pathogenesis, Jena, Germany.
Mandy KnüpferChair for Microbial Ecology, Institute for Food and Health (ZIEL), TUM School of Life Sciences, Technische Universität München, Freising, Germany.
Marcel KegelChair for Microbial Ecology, Institute for Food and Health (ZIEL), TUM School of Life Sciences, Technische Universität München, Freising, Germany.
Britta SpanierChair for Metabolic Programming, Institute for Food and Health (ZIEL), TUM School of Life Sciences, Technische Universität München, Freising, Germany.
Elisabeth M Liebler-TenorioFriedrich-Loeffler-Institut, Institute of Molecular Pathogenesis, Jena, Germany.
Thilo M FuchsFriedrich-Loeffler-Institut, Institute of Molecular Pathogenesis, Jena, Germany.ORCID 0000-0002-3056-1824
Friedrich-Loeffler-Institut · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The insecticidal toxin complex (Tc) proteins are produced by several insect-associated bacteria, including Yersinia enterocolitica strain W22703, which oscillates between two distinct pathogenicity phases in invertebrates and humans. The mechanism by which this high-molecular-weight toxin is released into the extracellular surrounding, however, has not been deciphered. In this study, we investigated the regulation and functionality of a phage-related holin/endolysin (HE) cassette located within the insecticidal pathogenicity island Tc-PAI

Indexed as

Bacterial ToxinsInsecticidesMothsYersinia enterocoliticaAnimalsBacterial ProteinsCaenorhabditis elegansEndopeptidasesHumansInsectaLuciferasesBacterial ProteinsBacterial ToxinsendolysinEndopeptidasesInsecticidesLuciferasesCaenorhabditis elegansendolysinGalleria mellonellaholininsecticidal toxinlysis cassetteT10SSTcaAYersinia enterocolitica

Identifiers

PMID37184385
PMCPMC10304863
OpenAlexW4376617155

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.