Evidence map›Paper›PMID 37184383›Full record

ArticleInfection and immunity2023

Histoplasma capsulatum Relies on Tryptophan Biosynthesis To Proliferate within the Macrophage Phagosome.

Qian Shen, Alondra Gonzalez-Mireles, Stephanie C Ray, Chad A Rappleye

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Fungal Infections in Disorders of Inborn Errors of Immunity.Clinical reviews in allergy & immunology · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Genotypic diversity, virulence, and molecular genetic tools inMicrobiology and molecular biology reviews : MMBR · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Qian ShenRhodes College, Department of Biology, Memphis, Tennessee, USA.ORCID 0000-0002-9001-7636
Alondra Gonzalez-MirelesRhodes College, Department of Biology, Memphis, Tennessee, USA.
Stephanie C RayOhio State University, Department of Microbiology, Columbus, Ohio, USA.
Chad A RappleyeOhio State University, Department of Microbiology, Columbus, Ohio, USA.ORCID 0000-0001-7880-5958
Rhodes College · USThe Ohio State University · US

Funding

Intracellular Proliferation of the fungal pathogen Histoplasma capsulatumR01AI148561 · NIAID · OHIO STATE UNIVERSITY · PI Chad A Rappleye · 2020 to 2026
$2.5M
NIAID NIH HHS R01 AI148561
6 · The paper itself

Abstract

Histoplasma capsulatum yeasts reside and proliferate within the macrophage phagosome during infection. This nutrient-depleted phagosomal environment imposes challenges to

Indexed as

HistoplasmaHistoplasmosisAmino Acids, AromaticMacrophagesPhagosomesTyrosineAmino Acids, AromaticTyrosinearomatic amino acidsHistoplasmaintracellular pathogensmacrophagespathogenesisphagosomestryptophan biosynthesisvirulence

Identifiers

PMID37184383
PMCPMC10269170
OpenAlexW4376617197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.