Evidence map›Paper›PMID 37184061›Full record

ArticleeLife2023

Precise temporal control of neuroblast migration through combined regulation and feedback of a Wnt receptor.

Erik S Schild, Shivam Gupta, Clément Dubois, Euclides E Fernandes Póvoa, Marie-Anne Félix, Andrew Mugler, Hendrik C Korswagen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Single-cell transcriptomic profiling ofbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. MAB-5/Hox regulates the Q neuroblast transcriptome, includingbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Erik S SchildHubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, Netherlands.
Shivam GuptaDepartment of Physics and Astronomy, Purdue University, West Lafayette, United States.
Clément DuboisInstitut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Paris, France.
Euclides E Fernandes PóvoaHubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, Netherlands.ORCID 0000-0002-0920-7783
Marie-Anne FélixInstitut de Biologie de l'Ecole Normale Supérieure, CNRS, INSERM, Paris, France.
Andrew MuglerDepartment of Physics and Astronomy, Purdue University, West Lafayette, United States.ORCID 0000-0001-9367-7026
Hendrik C KorswagenHubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, Netherlands.ORCID 0000-0001-7931-4472
Royal Netherlands Academy of Arts and Sciences · NLInserm · FRPurdue University West Lafayette · USUniversity of Pittsburgh · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Many developmental processes depend on precise temporal control of gene expression. We have previously established a theoretical framework for regulatory strategies that can govern such high temporal precision, but experimental validation of these predictions was still lacking. Here, we use the time-dependent expression of a Wnt receptor that controls neuroblast migration in

Indexed as

Caenorhabditis elegans ProteinsTranscription FactorsAnimalsCaenorhabditis elegansCell MovementFeedbackGene Expression Regulation, DevelopmentalCaenorhabditis elegans ProteinsTranscription Factorsbiological timerC. eleganscell migrationcomputational biologydevelopmental biologygene regulationsystems biologytiming precision

Identifiers

PMID37184061
PMCPMC10259474
OpenAlexW4376613028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.