Evidence map›Paper›PMID 37183806›Full record

ArticleNano letters2023

Neutralization of Intracellular pH Homeostasis to Inhibit Osteoclasts Based on a Spatiotemporally Selective Delivery System.

Hongsen Tian, Chenhui Gu, Wenshuai Li, Tong Tong, Yunsheng Wang, Yang Yang, Haoli Wang, Zhanqiu Dai, Pengfei Chen, Feng Wang and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Nano letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Application and prospects of nanomaterials in osteoporosis treatment.International journal of pharmaceutics: X · 2026
    Review
  3. Article
  4. Article
  5. Review
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  7. Review
  8. KMaterials today. Bio · 2025
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Hongsen TianDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.
Chenhui GuKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.ORCID 0000-0002-8698-9395
Wenshuai LiDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.
Tong TongDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.
Yunsheng WangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.
Yang YangKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.
Haoli WangKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.
Zhanqiu DaiKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.
Pengfei ChenKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.
Feng WangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.
Xianfeng LinKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.ORCID 0000-0003-1871-774X
Liqing ShangguanKey Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang Province, Hangzhou, Zhejiang 310016, China.
Linfeng WangDepartment of Spine Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050000, China.ORCID 0009-0008-9368-2069
Sir Run Run Shaw Hospital · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is a global disease caused by abnormal overactivation of osteoclasts. The acidic environment in sealing zone of osteoclasts with H

Indexed as

OsteoclastsOsteoporosisHomeostasisHumansHydrogen-Ion Concentrationintracellular pHmembrane hybridizationnanovesiclesosteoclastsosteoporosis

Identifiers

PMID37183806
PMCPMC10214447
OpenAlexW4376614060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.