ArticleCerebral cortex (New York, N.Y. : 1991)2023
Expectation violations produce error signals in mouse V1.
Article in Cerebral cortex (New York, N.Y. : 1991), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Intrinsic timing, not temporal prediction, underlies ramping dynamics in visual and parietal cortex during passive behavior.Science advances · 2026Article
- Contrasting predictive coding and representational accounts of perceptual organization, stimulus predictability, and attentional modulation in the visual cortical hierarchy.Neuroscience of consciousness · 2026Review
- Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination.PLoS biology · 2025Article
- The visual evoked potential is a sensitive and powerful measure of experience-dependent visual cortical plasticity in mice.Current opinion in neurobiology · 2025Review
- Oddball Evoked Deviant Responses Reflect Complex Context-Dependent Expectations in Mouse V1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Learning predictive signals within a local recurrent circuit.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Prediction of future input explains lateral connectivity in primary visual cortex.Current biology : CB · 2025Article
- M2 receptors are required for spatiotemporal sequence learning in mouse primary visual cortex.Journal of neurophysiology · 2024Article
- Repeated passive visual experience modulates spontaneous and non-familiar stimuli-evoked neural activity.Scientific reports · 2023Article
- Efficient Temporal Coding in the Early Visual System: Existing Evidence and Future Directions.Frontiers in computational neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Repeated exposure to visual sequences changes the form of evoked activity in the primary visual cortex (V1). Predictive coding theory provides a potential explanation for this, namely that plasticity shapes cortical circuits to encode spatiotemporal predictions and that subsequent responses are modulated by the degree to which actual inputs match these expectations. Here we use a recently developed statistical modeling technique called Model-Based Targeted Dimensionality Reduction (MbTDR) to study visually evoked dynamics in mouse V1 in the context of an experimental paradigm called "sequence learning." We report that evoked spiking activity changed significantly with training, in a manner generally consistent with the predictive coding framework. Neural responses to expected stimuli were suppressed in a late window (100-150 ms) after stimulus onset following training, whereas responses to novel stimuli were not. Substituting a novel stimulus for a familiar one led to increases in firing that persisted for at least 300 ms. Omitting predictable stimuli in trained animals also led to increased firing at the expected time of stimulus onset. Finally, we show that spiking data can be used to accurately decode time within the sequence. Our findings are consistent with the idea that plasticity in early visual circuits is involved in coding spatiotemporal information.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.