ArticleNeurobiology of learning and memory2023
Acute stress persistently alters instrumental motivation without affecting appetitive Pavlovian conditioning, extinction, or contextual renewal.
Article in Neurobiology of learning and memory, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 6 citations in OpenAlex.
- Sexually dimorphic effects of single prolonged stress on conditioned suppression behavior in Long Evans rats with no detection of altered mRNA expression of VGLUT1, GAD1, and Arc in the ventral hippocampus.Frontiers in behavioral neuroscience · 2026Article
- Stress induces distinct social behavior states encoded by the ventral hippocampus.bioRxiv : the preprint server for biology · 2025Article
- Beyond reconsolidation: The need for a broad theoretical approach in clinical translations of research on retrieval-induced plasticity.Behavioral neuroscience · 2024Review
- Sex-dependent effects of acute stress in adolescence or adulthood on appetitive motivation.Psychopharmacology · 2024Article
- Stress, associative learning, and decision-making.Neurobiology of learning and memory · 2023Review
- Pharmacological activation of the amygdala, but not single prolonged footshock-induced acute stress, interferes with cue-induced motivation toward food rewards in rats.Frontiers in behavioral neuroscience · 2023Article
- Sex and estrous cycle effects on stress-enhanced fear learning in Long-Evans rats.Learning & memory (Cold Spring Harbor, N.Y.)Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
In two experiments, we adapted the stress-enhanced fear learning approach to evaluate the persistent effects of acute stress on appetitive learning and motivation in adult male Long Evans rats. In Experiment 1, we found that exposure to a battery of footshocks in one context had no effect on the acquisition, extinction, or contextual renewal of an appetitive Pavlovian discrimination in different contexts. However, when rats were subsequently trained to respond on a progressive ratio instrumental schedule, rats with a history of shock showed lower response rates and progressive ratio break points. Extinction of the shock-associated context had little effect on progressive ratio responding. In Experiment 2, we replicated this instrumental responding deficit with a continuous reinforcement schedule when the Pavlovian phases did not intervene in the time between shock and instrumental testing. Our findings here demonstrate that highly stressful acute experiences produce long-lasting deficits in instrumental motivation for food in male rats.
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