Evidence map›Paper›PMID 37182549›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2023

Co-infection of Leishmania infantum and a Crithidia-related species in a case of refractory relapsed visceral leishmaniasis with non-ulcerated cutaneous manifestation in Brazil.

Luana Aparecida Rogerio, Talita Yuri Takahashi, Luria Cardoso, Nayore Tamie Takamiya, Enaldo Vieira de Melo, Amelia Ribeiro de Jesus, Fabricia Alvisi de Oliveira, Sarah Forrester, Daniel C Jeffares, João Santana da Silva and 3 more

Abstract readCase Reports
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Microorganisms · 2025
    Article
  3. Article
  4. Molecular characterization ofOpen veterinary journal · 2025
    Article
  5. Article
  6. Article
  7. Genomes ofPathogens (Basel, Switzerland) · 2023
    Article
  8. Article
  9. Natural infection withFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Luana Aparecida RogerioDepartment of Genetics and Evolution, Centre for Biological Sciences and Health, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil.
Talita Yuri TakahashiDepartment of Genetics and Evolution, Centre for Biological Sciences and Health, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil.
Luria CardosoDepartment of Medicine, Centre for Biology and Health Sciences, Federal University of Sergipe (UFS), Aracaju, Sergipe, Brazil.
Nayore Tamie TakamiyaDepartment of Genetics and Evolution, Centre for Biological Sciences and Health, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil.
Enaldo Vieira de MeloDepartment of Medicine, Centre for Biology and Health Sciences, Federal University of Sergipe (UFS), Aracaju, Sergipe, Brazil.
Amelia Ribeiro de JesusDepartment of Medicine, Centre for Biology and Health Sciences, Federal University of Sergipe (UFS), Aracaju, Sergipe, Brazil.
Fabricia Alvisi de OliveiraLaboratory of Molecular Biology, University Hospital (HU-UFS), Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Sarah ForresterDepartment of Biology and York Biomedical Research Institute, University of York, York, UK.
Daniel C JeffaresDepartment of Biology and York Biomedical Research Institute, University of York, York, UK.
João Santana da SilvaFiocruz - Bi-Institutional Translational Medicine Project, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
José Marcos RibeiroNational Institute of Health NIH/NIAID, Rockville, Maryland, United States.
Roque Pacheco AlmeidaDepartment of Medicine, Centre for Biology and Health Sciences, Federal University of Sergipe (UFS), Aracaju, Sergipe, Brazil.
Sandra Regina MaruyamaDepartment of Genetics and Evolution, Centre for Biological Sciences and Health, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil. Electronic address: sandrarcm@ufscar.br.

Funding

Vector-Borne Diseases: Biology Of Vector Host RelationshipZIAAI000810 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI RIBEIRO, JOSE · 2009 to 2025
$20.8M
Vector-Borne Diseases: Molecular Mechanisms in Vector-Host InteractionsZIAAI001012 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI RIBEIRO, JOSE · 2009 to 2025
$9.4M
Vector-Borne Diseases: Biology Of Vector Host RelationshipZ01AI000810 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI RIBEIRO, JOSE M · 1997 to 2008
$3.5M
Vector-Borne Diseases: Molecular Mechanisms in Vector-Host InteractionsZ01AI001012 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI RIBEIRO, JOSE · 2007 to 2008
$1.5M
Intramural NIH HHS Z01 AI000810Intramural NIH HHS Z01 AI001012Intramural NIH HHS ZIA AI000810Intramural NIH HHS ZIA AI001012Intramural NIH HHS ZIA AI001201Medical Research Council MR/T016019/1
6 · The paper itself

Abstract

We report a refractory and relapsed visceral leishmaniasis case in a male child patient followed from 2016 to 2020, whose clinical isolates from multiple relapses were analyzed at the genome level. To the best of our knowledge, it is the first report that both visceral leishmaniasis and non-ulcerated cutaneous leishmaniasis have concomitantly manifested in the same patient. Importantly, sequence analysis revealed that the patient was co-infected with Leishmania infantum and a Crithidia-related parasite, which was previously found in a fatal case of visceral leishmaniasis from the same endemic region.

Indexed as

CoinfectionLeishmania infantumLeishmaniasis, CutaneousLeishmaniasis, VisceralBrazilChildCrithidiaHumansMaleCrithidia spLeishmania infantumNon-ulcerated cutaneous leishmaniasis (NUCL)Trypanosomatid co-infectionVisceral leishmaniasis (VL)Whole-genome sequencing analysis

Identifiers

PMID37182549
PMCPMC10330508

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.