Evidence map›Paper›PMID 37181830›Full record

ReviewSovremennye tekhnologii v meditsine2022

Scaffolds Based on Poly(3-Hydroxybutyrate) and Its Copolymers for Bone Tissue Engineering (Review).

A P Bonartsev, V V Voinova, A V Volkov, A A Muraev, E M Boyko, A A Venediktov, N N Didenko, A A Dolgalev

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Sovremennye tekhnologii v meditsine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

A P BonartsevAssociate Professor, Department of Bioengineering, Faculty of Biology; Lomonosov Moscow State University, 1-12 Leninskiye Gory, Moscow, 119234, Russia.
V V VoinovaSenior Researcher, Department of Biochemistry, Faculty of Biology; Lomonosov Moscow State University, 1-12 Leninskiye Gory, Moscow, 119234, Russia.
A V VolkovSenior Researcher; N.N. Priorov National Medical Research Center of Traumatology and Orthopedics, 10 Priorova St., Moscow, 127299, Russia; Associate Professor, Department of Pathological Anatomy, Medical Institute; Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
A A MuraevProfessor, Department of Maxillofacial Surgery and Surgical Dentistry; Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
E M BoykoTeacher, Essentuki Branch; Stavropol State Medical University, 310 Mira St., Stavropol, 355017, Russia.
A A VenediktovDirector; Cardioplant LLC, 1B Tsentralnaya St., Bldg. 2, Penza, 440004, Russia.
N N DidenkoAssistant, Department of Pathological Physiology; Stavropol State Medical University, 310 Mira St., Stavropol, 355017, Russia.
A A DolgalevAssociate Professor, Professor, Department of General and Pediatric Dentistry; Stavropol State Medical University, 310 Mira St., Stavropol, 355017, Russia; Head of the Center for Innovation and Technology Transfer of the Research and Innovation Association; Stavropol State Medical University, 310 Mira St., Stavropol, 355017, Russia.
Pathological Society · GBLomonosov Moscow State University · RUCentral Scientific Research Institute of Traumatology and Orthopedics · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biodegradable and biocompatible polymers are actively used in tissue engineering to manufacture scaffolds. Biomedical properties of polymer scaffolds depend on the physical and chemical characteristics and biodegradation kinetics of the polymer material, 3D microstructure and topography of the scaffold surface, as well as availability of minerals, medicinal agents, and growth factors loaded into the scaffold. However, in addition to the above, the intrinsic biological activity of the polymer and its biodegradation products can also become evident. This review provides studies demonstrating that scaffolds made of poly(3-hydroxybutyrate) (PHB) and its copolymers have their own biological activity, and namely, osteoinductive properties. PHB can induce differentiation of mesenchymal stem cells in the osteogenic direction

Indexed as

Tissue EngineeringTissue Scaffolds3-Hydroxybutyric AcidPolyestersPolyhydroxybutyratesPolymers3-Hydroxybutyric Acidpoly-beta-hydroxybutyratePolyestersPolyhydroxybutyratesPolymersbone defectsbone regenerationmatricesmesenchymal stem cellsosteoinductive propertiespoly(3-hydroxybutyrate)polyhydroxyalkanoatesscaffolds

Identifiers

PMID37181830
PMCPMC10171059
OpenAlexW4307687284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.