Evidence map›Paper›PMID 37181809›Full record

ReviewMediators of inflammation2023

Effects of Ferroptosis on Cardiovascular Diseases.

Jiayi Xu, Jinkui Pi, Yanjing Zhang, Jinhan Zhou, Shuxia Zhang, Sisi Wu

Open access · goldAbstract readReview
In one paragraph

Review in Mediators of inflammation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiayi XuCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.ORCID https://orcid.org/0000-0002-4830-7648
Jinkui PiCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Yanjing ZhangCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Jinhan ZhouCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Shuxia ZhangCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.
Sisi WuCore Facilities, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.ORCID https://orcid.org/0000-0002-3791-9534
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a novel form of programmed cell death characterized by the accumulation of iron-dependent lipid peroxides, which causes membrane injury. Under the catalysis of iron ions, cells deficient in glutathione peroxidase (GPX4) cannot preserve the balance in lipid oxidative metabolism, and the buildup of reactive oxygen species on the membrane lipids leads to cell death. An increasing body of evidence suggests that ferroptosis plays a significant role in the development and occurrence of cardiovascular diseases. In this paper, we mainly elaborated on the molecular mechanisms regulating ferroptosis and its impact on cardiovascular disease to lay the groundwork for future studies on the prophylaxis and treatment of this patient population.

Indexed as

Cardiovascular DiseasesFerroptosisApoptosisHumansIronLipid PeroxidationIron

Identifiers

PMID37181809
PMCPMC10175025
OpenAlexW4368341661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.