ArticleChemical science2023
The role of analyte concentration in accelerated reaction rates in evaporating droplets.
Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed.
- Contact Electrification of Individual Water Microdroplets Inside Mass Spectrometers Leads to Extensive Oxidation or Reduction Irrespective of Initial Droplet Charge or Polarity.ACS central science · 2026Article
- Surface tension measurements reveal charge-driven surfactant depletion in microdroplets approaching the Rayleigh limit.Chemical science · 2026Article
- Dark Reactions in Microdroplets Explain Widespread Artifacts in Metabolomic Profiling.ACS measurement science au · 2026Article
- Enhancement of Esterification Reaction Rates in Solvent-Free Aerosol Droplets.Journal of the American Chemical Society · 2026Article
- Atmospheric Sampling Mass Spectrometers Activate and Ionize Neutral Water Microdroplets to MeV Energies and up to 200,000+ Charges: Implications for Water Stability and Unusual Chemistry in Microdroplets.ACS central science · 2025Article
- Liquid Crystal-Driven Chemical Feeding Accelerates Condensation Reactions in Droplet Microreactors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A compact cassette tape for DNA-based data storage.Science advances · 2025Article
- An Alternative Explanation for Ions Put Forth as Evidence for Abundant Hydroxyl Radicals Formed Due to the Intrinsic Electric Field at the Surface of Water Droplets.Analytical chemistry · 2025Article
- Role of Interfacial Processes in Accelerated Reactions in Nano- and Microdroplets.The journal of physical chemistry. A · 2025Article
- Evidence on Interfacial Reaction Governing NOEnvironmental science & technology · 2025Article
- Spontaneous Fission of Charged Water Nanodrops: Unveiling the Stochastic Nature of Fission Pathways and Dynamics.Journal of the American Chemical Society · 2025Article
- Spontaneous Oxidation of Nitrous Acid to Nitric Acid in Supermicron Aqueous Droplets Is Acid-Accelerated.ACS earth & space chemistry · 2025Article
- A Source of the MysteriousACS central science · 2025Article
- Rapid and Sensitive Chemical Analysis of Individual Picolitre Droplets by Mass Spectrometry.Analytical chemistry · 2025Article
- Reaction acceleration at the surface of a levitated droplet by vapor dosing from a partner droplet.Chemical science · 2024Article
- Rapid analysis of untreated food samples by gel loading tip spray ionization mass spectrometry.Analytical and bioanalytical chemistry · 2024Article
- Accelerating protein aggregation and amyloid fibrillation for rapid inhibitor screening.Chemical science · 2024Article
- Examining DNA Structures with In-droplet Hydrogen/Deuterium Exchange Mass Spectrometry.International journal of mass spectrometry · 2024Article
- Effects of Nano-Electrospray Ionization Emitter Position on Unintentional In-Source Activation of Peptide and Protein Ions.Journal of the American Society for Mass Spectrometry · 2024Article
- Oxazolone mediated peptide chain extension and homochirality in aqueous microdroplets.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accelerated reactions in microdroplets have been reported for a wide range of reactions with some microdroplet reactions occurring over a million times faster than the same reaction in bulk solution. Unique chemistry at the air-water interface has been implicated as a primary factor for accelerated reaction rates, but the role of analyte concentration in evaporating droplets has not been as well studied. Here, theta-glass electrospray emitters and mass spectrometry are used to rapidly mix two solutions on the low to sub-microsecond time scale and produce aqueous nanodrops with different sizes and lifetimes. We demonstrate that for a simple bimolecular reaction where surface chemistry does not appear to play a role, reaction rate acceleration factors are between 10
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.