Evidence map›Paper›PMID 37181717›Full record

ArticleFrontiers in public health2023

Effect of mobile health reminders on tuberculosis treatment outcomes in Shanghai, China: A prospective cohort study.

Zheyuan Wu, Liping Lu, Yong Li, Jing Chen, Zurong Zhang, Chenxi Ning, Zheng'an Yuan, Qichao Pan, Xin Shen, Wenhong Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 5 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Zheyuan WuDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Liping LuSongjiang District Center for Disease Control and Prevention, Shanghai, China.
Yong LiSongjiang District Center for Disease Control and Prevention, Shanghai, China.
Jing ChenDepartment of Tuberculosis Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Zurong ZhangDepartment of Tuberculosis Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Chenxi NingDepartment of Tuberculosis Control, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Zheng'an YuanShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Qichao PanShanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
Xin ShenShanghai Institutes of Preventive Medicine, Shanghai, China.
Wenhong ZhangDepartment of Infectious Diseases, Huashan Hospital, Fudan University, Shanghai, China.
Shanghai Municipal Center For Disease Control Prevention · CNFudan University · CNSongjiang District Central Hospital · CNShanghai Institute of Hematology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Poor adherence increases the risk of unfavorable outcomes for tuberculosis (TB) patients. Mobile health (mHealth) reminders become promising approaches to support TB patients' treatment. But their effects on TB treatment outcomes remain controversial. In this prospective cohort study, we evaluated the effect of the reminder application (app) and the smart pillbox on TB treatment outcomes compared with the standard care in Shanghai, China. Methods: We recruited new pulmonary TB (PTB) patients diagnosed between April and November 2019 who were aged 18 or above, treated with the first-line regimen (2HREZ/4HR), and registered at Songjiang CDC (Shanghai). All eligible patients were invited to choose the standard care, the reminder app, or the smart pillbox to support their treatment. Cox proportional hazard model was fitted to assess the effect of mHealth reminders on treatment success. Results: 260 of 324 eligible patients enrolled with 88 using standard care, 82 the reminder app, and 90 the smart pillbox, followed for a total of 77,430 days. 175 (67.3%) participants were male. The median age was 32 (interquartile range [IQR] 25 to 50) years. A total of 44,785 doses were scheduled for 172 patients in the mHealth reminder groups during the study period. 44,604 (99.6%) doses were taken with 39,280 (87.7%) monitored by the mHealth reminders. A significant time-dependent downward linear trend was observed in the monthly proportion of dose intake ( Conclusion: The reminder app and the smart pillbox interventions were acceptable and improved the treatment outcomes compared with the standard care under the programmatic setting in Shanghai, China. More high-level evidence is expected to confirm the effect of mHealth reminders on TB treatment outcomes.

Indexed as

TelemedicineTuberculosisAdultChinaFemaleHumansMaleMiddle AgedProspective StudiesReminder SystemsTreatment Outcomedigital healthmedication monitormobile applicationtreatment outcometuberculosis

Identifiers

PMID37181717
PMCPMC10173861
OpenAlexW4367187446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.