Evidence map›Paper›PMID 37181697›Full record

ArticleFrontiers in public health2023

ChatGPT and the rise of large language models: the new AI-driven infodemic threat in public health.

Luigi De Angelis, Francesco Baglivo, Guglielmo Arzilli, Gaetano Pierpaolo Privitera, Paolo Ferragina, Alberto Eugenio Tozzi, Caterina Rizzo

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. [Medical education and artificial intelligence: perspectives and ethical challenges].Revista medica del Instituto Mexicano del Seguro Social · 2025
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  8. An expert-based assessment of the quality, reliability, understandability, and readability of ChatGPT responses on cerebral palsy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
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  11. Assessment of ChatGPT's Performance on the ACP 2024 National Prosthodontics Resident Exam (NPRE).European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
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  12. Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator-Generated Multiple-Choice Questions in a Dental Exam.European journal of dental education : official journal of the Association for Dental Education in Europe · 2026
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150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Luigi De AngelisDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Francesco BaglivoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Guglielmo ArzilliDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Gaetano Pierpaolo PriviteraDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Paolo FerraginaDepartment of Computer Science, University of Pisa, Pisa, Italy.
Alberto Eugenio TozziFetal, Neonatal and Cardiologic Science Research Area, Predictive and Preventive Medicine Research Unit, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Caterina RizzoDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Large Language Models (LLMs) have recently gathered attention with the release of ChatGPT, a user-centered chatbot released by OpenAI. In this perspective article, we retrace the evolution of LLMs to understand the revolution brought by ChatGPT in the artificial intelligence (AI) field. The opportunities offered by LLMs in supporting scientific research are multiple and various models have already been tested in Natural Language Processing (NLP) tasks in this domain. The impact of ChatGPT has been huge for the general public and the research community, with many authors using the chatbot to write part of their articles and some papers even listing ChatGPT as an author. Alarming ethical and practical challenges emerge from the use of LLMs, particularly in the medical field for the potential impact on public health. Infodemic is a trending topic in public health and the ability of LLMs to rapidly produce vast amounts of text could leverage misinformation spread at an unprecedented scale, this could create an "AI-driven infodemic," a novel public health threat. Policies to contrast this phenomenon need to be rapidly elaborated, the inability to accurately detect artificial-intelligence-produced text is an unresolved issue.

Indexed as

Artificial IntelligenceInfodemicLanguageNatural Language ProcessingPublic Healthartificial intelligenceChatGPTinfodemiclarge language modelsnatural language processingpublic health

Identifiers

PMID37181697
PMCPMC10166793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.