Evidence map›Paper›PMID 37181660›Full record

ArticleComputational and structural biotechnology journal2023

Sequential targeting biomimetic nano platform for enhanced mild photothermal therapy and chemotherapy of tumor.

Lianfu Wang, Manxiang Wu, Yuning Pan, Dong Xie, Chengyuan Hong, Jianbin Li, Xuehua Ma, Huachun Xu, Huayu Li, Tianxiang Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Lianfu WangDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Manxiang WuDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Yuning PanDepartment of Radiology, The First Affiliated Hospital of Ningbo University, Ningbo 315010, China.
Dong XieDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Chengyuan HongCixi Institute of Biomedical Engineering, International Cooperation Base of Biomedical Materials Technology and Application, Chinese Academy of Science (CAS) Key Laboratory of Magnetic Materials and Devices, Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Institute of Materials Technology and Engineering, CAS, 1219 Zhongguan West Road, Ningbo 315201, China.
Jianbin LiDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Xuehua MaCixi Institute of Biomedical Engineering, International Cooperation Base of Biomedical Materials Technology and Application, Chinese Academy of Science (CAS) Key Laboratory of Magnetic Materials and Devices, Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Institute of Materials Technology and Engineering, CAS, 1219 Zhongguan West Road, Ningbo 315201, China.
Huachun XuDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Huayu LiDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Tianxiang ChenCixi Institute of Biomedical Engineering, International Cooperation Base of Biomedical Materials Technology and Application, Chinese Academy of Science (CAS) Key Laboratory of Magnetic Materials and Devices, Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Institute of Materials Technology and Engineering, CAS, 1219 Zhongguan West Road, Ningbo 315201, China.
Aiguo WuCixi Institute of Biomedical Engineering, International Cooperation Base of Biomedical Materials Technology and Application, Chinese Academy of Science (CAS) Key Laboratory of Magnetic Materials and Devices, Zhejiang Engineering Research Center for Biomedical Materials, Ningbo Institute of Materials Technology and Engineering, CAS, 1219 Zhongguan West Road, Ningbo 315201, China.
Qiang LiDepartment of Radiology, The Affiliated People's Hospital, Ningbo University, Ningbo 315040, China.
Ji Hua Laboratory · CNNingbo University Affiliated Hospital · CNNingbo University · CNUniversity of Nottingham Ningbo China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor targeting drug delivery is of significant importance for the treatment of triple negative breast cancer (TNBC) considering the presence of appreciable amount of tumor matrix and the absence of effective targets on the tumor cells. Hence in this study, a new therapeutic multifunctional nanoplatform with improved TNBC targeting ability and efficacy was constructed and used for therapy of TNBC. Specifically, curcumin loaded mesoporous polydopamine (mPDA/Cur) nanoparticles were synthesized. Thereafter, manganese dioxide (MnO

Indexed as

Cell membranesChemotherapyPhotothermal therapyPolydopamineTriple negative breast cancer

Identifiers

PMID37181660
PMCPMC10172638
OpenAlexW4367057099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.