Evidence map›Paper›PMID 37181632›Full record

ArticleRSC chemical biology2023

A monoadduct generating Ru(ii) complex induces ribosome biogenesis stress and is a molecular mimic of phenanthriplatin.

Richard J Mitchell, Sarah M Kriger, Alexander D Fenton, Dmytro Havrylyuk, Ankit Pandeya, Yang Sun, Tami Smith, Jason E DeRouchey, Jason M Unrine, Viral Oza and 4 more

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Richard J MitchellDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.
Sarah M KrigerDepartment of Chemistry, North Carolina State University 2620 Yarbrough DriveRaleigh NC 27695 USA eglazer@ncsu.edu.
Alexander D FentonDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.
Dmytro HavrylyukDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.
Ankit PandeyaDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.
Yang SunDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.
Tami SmithDepartment of Plant and Soil Sciences, University of Kentucky 1100 S. Limestone St Lexington KY 40546 USA.
Jason E DeRoucheyDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.ORCID https://orcid.org/0000-0002-3624-4432
Jason M UnrineDepartment of Plant and Soil Sciences, University of Kentucky 1100 S. Limestone St Lexington KY 40546 USA.ORCID https://orcid.org/0000-0003-3012-5261
Viral OzaDepartment of Molecular and Cellular Biochemistry, University of Kentucky 741 S. Limestone St. Lexington KY 40536 USA.
Jessica S BlackburnDepartment of Molecular and Cellular Biochemistry, University of Kentucky 741 S. Limestone St. Lexington KY 40536 USA.
Yinan WeiDepartment of Chemistry, University of Kentucky 505 Rose St. Lexington KY 40506 USA ec.glazer@uky.edu david.heidary@gmail.com.ORCID https://orcid.org/0000-0002-9936-7149
David K HeidaryDepartment of Chemistry, North Carolina State University 2620 Yarbrough DriveRaleigh NC 27695 USA eglazer@ncsu.edu.ORCID https://orcid.org/0000-0001-6008-4216
Edith C GlazerDepartment of Chemistry, North Carolina State University 2620 Yarbrough DriveRaleigh NC 27695 USA eglazer@ncsu.edu.ORCID https://orcid.org/0000-0002-0190-7742
University of Kentucky · USNorth Carolina State University · US

Funding

University of Kentucky Markey Cancer Center Support Grant ECIA SupplementP30CA177558 · NCI · UNIVERSITY OF KENTUCKY · PI Jennifer F Rogers · 2013 to 2026
$38.3M
NCI NIH HHS P30 CA177558
6 · The paper itself

Abstract

Ruthenium complexes are often investigated as potential replacements for platinum-based chemotherapeutics in hopes of identifying systems with improved tolerability

Identifiers

PMID37181632
PMCPMC10170627
OpenAlexW4322577194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.