Evidence map›Paper›PMID 37181560›Full record

ArticleFrontiers in neurology2023

Connection between right-to-left shunt and photosensitivity: a community-based cross-sectional study.

Bosi Dong, Shuming Ji, Yajiao Li, Hua Li, Ruiqi Yang, Na Yang, Zhu Liu, Chenxing Zhu, Hui Wang, Yusha Tang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Bosi DongDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Shuming JiDepartment of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, China.
Yajiao LiDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Hua LiDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Ruiqi YangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Na YangDepartment of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, China.
Zhu LiuDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Chenxing ZhuDepartment of Clinical Research Management, West China Hospital, Sichuan University, Chengdu, China.
Hui WangDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Yusha TangDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Anjiao PengDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Lei ChenDepartment of Neurology, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypersensitivity to light is a common symptom associated with dysfunction of the occipital region. Earlier studies also suggested that clinically significant right-to-left shunt (RLS) could increase occipital cortical excitability associated with the occurrence of migraine. The aim of this study was to investigate the relationship between RLS and photosensitivity. Methods: This cross-sectional observational study included the residents aged 18-55 years living in the Mianzhu community between November 2021 and October 2022. Photosensitivity was evaluated using the Photosensitivity Assessment Questionnaire along with baseline clinical data through face-to-face interviews. After the interviews, contrast-transthoracic echocardiography (cTTE) was performed to detect RLS. Inverse probability weighting (IPW) was used to reduce selection bias. Photosensitivity score was compared between individuals with and without significant RLS using multivariable linear regression based on IPW. Results: A total of 829 participants containing 759 healthy controls and 70 migraineurs were finally included in the analysis. Multivariable linear regression analysis showed that migraine (β = 0.422; 95% CI: 0.086-0.759; Conclusion: RLS is associated with photosensitivity independently and might exacerbate photophobia in migraineurs. Future studies with RLS closure are needed to validate the findings. Trial registration: This study was registered at the Chinese Clinical Trial Register,

Indexed as

community-based studycross-sectional studymigrainephotosensitivityright-to-left shunt

Identifiers

PMID37181560
PMCPMC10172477
OpenAlexW4367185080

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.