ArticleCritical care explorations2023
The Association Between Time From Emergency Department Visit to ICU Admission and Mortality in Patients With Sepsis.
Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 11 citations in OpenAlex.
- Association between prolonged Emergency Department stay and Intensive Care Unit mortality among patients at a tertiary hospital in Ethiopia.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2026Article
- Direct admission to the intensive care unit for patients with prehospital septic shock is associated with a lower 30-day mortality rate.Scientific reports · 2026Article
- Trends and disparities in disseminated intravascular coagulation-related mortality among adults aged 25 and above in the U.S., 1999-2020: CDC WONDER insights.Thrombosis journal · 2026Article
- Epidemiology, Management, and Outcomes of Patients Hospitalized With Community-Acquired Infection in a Resource-Limited Setting in Southeast Asia: A Prospective Observational Study.Open forum infectious diseases · 2026Article
- Incident and predictors of 30-day mortality in critically ill patients after admission to the emergency department in the central region of Thailand: a prospective observational study.BMC health services research · 2026Observational
- Predicting ICU transfer for high-risk patients upon medical admission via the medical intensive care prediction score (MICAPS).BMC emergency medicine · 2026Article
- Combined lactate, base excess, and MEWS score as predictors of ICU transfer from the emergency department: a retrospective cohort study.Frontiers in medicine · 2026Article
- The 6-hour window: is the sepsis transfer guideline enough?Acute and critical care · 2025Article
- Analysis of Emergency Department-based Intensive Care Units on Coding and Revenue.The western journal of emergency medicine · 2025Article
- Closed intensive care units and sepsis patient outcomes: a secondary analysis of data from a multicenter prospective observational study in South Korea.Acute and critical care · 2025Article
- Prehospital point-of-care medication burden as a predictor of poor related outcomes in unselected acute diseases.Internal and emergency medicine · 2025Article
- Emergency critical care: closing the gap between onset of critical illness and intensive care unit admission.Wiener klinische Wochenschrift · 2024Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Surviving Sepsis Campaign Guidelines 2021 recommends that adult patients with sepsis requiring intensive care should be admitted to the ICU within 6 hours of their emergency department (ED) visits. However, there is limited evidence on whether 6 hours is the best target time for compliance with the sepsis bundle. We aimed to investigate the association between time from ED visits to ICU admission (i.e., ED length of stay [ED-LOS]) and mortality and identify the optimal ED-LOS for patients with sepsis.
designRetrospective cohort study.
settingThe Medical Information Mart for Intensive Care Emergency Department and Medical Information Mart for Intensive Care IV databases. PATIENTS: Adult patients (≥ 18 yr old) who were transferred from the ED to the ICU and subsequently diagnosed with sepsis based on the Sepsis-3 criteria within 24 hours of ICU admission.
interventionsNone. MEASUREMENTS AND MAIN
resultsAmong 1,849 patients with sepsis, we found a disproportionally higher mortality rate in patients immediately admitted to the ICU (e.g., < 2 hr). When using ED-LOS as a continuous variable, ED-LOS was not significantly associated with 28-day mortality (adjusted odds ratio [OR] per hour increase, 1.04; 95% CI, 0.96-1.13;
conclusionsEarlier admission to the ICU (e.g., within 3.3 hr of ED visits) was associated with lower 28-day mortality in patients with sepsis. Our findings suggest patients with sepsis who require intensive care may benefit from a more immediate ICU admission than 6 hours.
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