Evidence map›Paper›PMID 37181299›Full record

ArticleFood science & nutrition2023

Curcumin-loaded cockle shell-derived calcium carbonate nanoparticles ameliorates lead-induced neurotoxicity in rats via attenuation of oxidative stress.

Maryam Muhammad Mailafiya, Kabeer Abubakar, Samaila Musa Chiroma, Abubakar Danmaigoro, Tawfiq Y T Zyoud, Ezamin Bin Abdul Rahim, Mohamad Aris Mohd Moklas, Zuki Abu Bakar Zakaria

Abstract read
In one paragraph

Article in Food science & nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Unravelling lead-induced toxicity in mammals: the role of oxidative stress and apoptosis and their modulation by emerging therapeutic strategies.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Review
  2. Potential Antidote Against Lead Toxicity-A Review.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maryam Muhammad MailafiyaDepartment of Human Anatomy, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.ORCID https://orcid.org/0000-0003-1734-2288
Kabeer AbubakarDepartment of Human Anatomy, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.ORCID https://orcid.org/0000-0001-7552-0383
Samaila Musa ChiromaDepartment of Human Anatomy, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.ORCID https://orcid.org/0000-0001-9638-4931
Abubakar DanmaigoroDepartment of Veterinary Anatomy, Faculty of Veterinary Medicine Usman Danfodiyo University Sokoto Nigeria.
Tawfiq Y T ZyoudDepartment of Radiology, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.
Ezamin Bin Abdul RahimDepartment of Radiology, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.
Mohamad Aris Mohd MoklasDepartment of Human Anatomy, Faculty of Medicine and Health Sciences University Putra Malaysia Serdang Malaysia.ORCID https://orcid.org/0000-0002-9282-129X
Zuki Abu Bakar ZakariaDepartment of Preclinical Sciences Faculty of Veterinary Medicine University Putra Malaysia Serdang Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A substantial global health burden is associated with neurotoxicity caused by lead (Pb) exposure and the common mechanism of this toxicity is mainly via oxidative damage. Curcumin has remarkable pharmacological activities but remains clinically constrained due to its poor bioavailability when orally administered. Currently, cockle shell-derived calcium carbonate nanoparticle (CSCaCO

Indexed as

cockle shellcurcumindrug deliveryleadnanoparticlesneurotoxicityoxidative stress

Identifiers

PMID37181299
PMCPMC10171497

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.