Evidence map›Paper›PMID 37181280›Full record

ArticleResearch and practice in thrombosis and haemostasis2023

Social determinants of health in pulmonary embolism management and outcome in hospitals: Insights from the United States nationwide inpatient sample.

Ioannis T Farmakis, Luca Valerio, George Giannakoulas, Lukas Hobohm, Mary Cushman, Gregory Piazza, Stavros V Konstantinides, Stefano Barco

Open access · goldAbstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. How patient profile and hospital setting drive pulmonary embolism treatment modality.Journal of vascular surgery. Venous and lymphatic disorders · 2026
    Article
  5. Article
  6. Racial Disparities in Upper Gastrointestinal Hemorrhage Treatment.Journal of racial and ethnic health disparities · 2026
    Article
  7. Household Income Differences and Variations in Management and Outcomes of Patients With Acute Pulmonary Embolism.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Temporal trend in venous thromboembolism hospitalization rates in Brazil.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Ioannis T FarmakisCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Luca ValerioCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
George GiannakoulasDepartment of Cardiology, AHEPA University General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Greece.
Lukas HobohmCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Mary CushmanDivision of Hematology and Oncology, Department of Medicine, University of Vermont Larner College of Medicine, Burlington, Vermont, USA.
Gregory PiazzaDepartment of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Stavros V KonstantinidesCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Stefano BarcoCenter for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
University Medical Center of the Johannes Gutenberg University Mainz · DEAristotle University of Thessaloniki · GRBrigham and Women's Hospital · USDemocritus University of Thrace · GRJohannes Gutenberg University Mainz · DEPalmetto Hematology Oncology · USUniversity Hospital of Zurich · CH

Funding

Thrombosis and Bleeding Risk Assessment in Medical InpatientsR01HL141290 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Deirdra R Terrell, Neil Adrian Zakai · 2019 to 2026
$3.5M
NHLBI NIH HHS R01 HL141290
6 · The paper itself

Abstract

Background: The role of social determinants in the treatment and course of acute pulmonary embolism (PE) is understudied. Objective: To investigate the association between social determinants of health with in-hospital management and early clinical outcomes following acute PE. Methods: We identified hospitalizations of adults with acute PE discharge diagnosis from the nationwide inpatient sample (2016-2018). Multivariable regression was used to investigate the association between race/ethnicity, type of expected primary payer, and income with the use of advanced PE therapies (thrombolysis, catheter-directed treatment, surgical embolectomy, extracorporeal membrane oxygenation), length of stay, hospitalization charges, and in-hospital death. Results: A total of 1,124,204 hospitalizations with a PE diagnosis were estimated from the 2016-2018 nationwide inpatient sample, corresponding to a hospitalization rate of 14.9/10,000 adult persons-year. The use of advanced therapies was lower in Black and Asian/Pacific Islander (vs. White patients: adjusted odds ratio [OR Conclusion: We observed inequalities in advanced therapies used for acute PE and higher in-hospital mortality in races other than White. Low socioeconomic status was also associated with lesser use of advanced treatment modalities and greater in-hospital mortality. Future studies should further explore and consider the long-term impact of social inequities in PE management.

Indexed as

disparityinequalitypulmonary embolismsocial determinants of health

Identifiers

PMID37181280
PMCPMC10173008
OpenAlexW4362663319

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.