Evidence map›Paper›PMID 37180904›Full record

ArticleHeliyon2023

Anti-inflammatory effect of glycyrrhetinic acid in IL-1β-induced SW982 cells and adjuvant-induced arthritis.

Yang Song, Xinyu Xing, Jing Shen, Guo Chen, Li Zhao, Lu Tian, Jie Ying, Yongqiang Yu

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Laboratory-selected, probioticFrontiers in nutrition · 2026
    Trial
  2. Dual-Targeted Inhibition of PARNanomaterials (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
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  6. Effect ofFrontiers in veterinary science · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yang SongDepartment of Pain, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Xinyu XingDepartment of Pain, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Jing ShenDepartment of Pain, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Guo ChenDepartment of Gynecology, Maternity and Child Health Hospital Affiliated to Anhui Medical University, Anhui Province Maternity and Child Health Hospital, No. 15 Yimin Street, Hefei 230001, Anhui, China.
Li ZhaoDepartment of Pain, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China.
Lu TianDepartment of Gynecology, Maternity and Child Health Hospital Affiliated to Anhui Medical University, Anhui Province Maternity and Child Health Hospital, No. 15 Yimin Street, Hefei 230001, Anhui, China.
Jie YingDepartment of Gynecology, Maternity and Child Health Hospital Affiliated to Anhui Medical University, Anhui Province Maternity and Child Health Hospital, No. 15 Yimin Street, Hefei 230001, Anhui, China.
Yongqiang YuDepartment of Radiology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei 230032, Anhui, China.
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influences of Glycyrrhetinic acid on expression of inflammatory factors in interleukin (IL)-1β-induced SW982 cells and its anti-inflammatory effects were discussed in this study. MTT results showed that Glycyrrhetinic acid (≤80 μmol·L-1) almost has no toxicity on SW982 cells. The results of ELISA and real-time PCR showed that Glycyrrhetinic acid (10, 20 and 40 μmol · L-1) can significantly inhibit the expression of inflammatory factors such as IL-6, IL-8 and matrix metalloproteinase-1 (MMP-1). Western blot analysis showed that Glycyrrhetinic acid remarkably blocked the NF-κB signaling pathway

Indexed as

AIAAnti-InflammatoryGlycyrrhetinic acidNF-κB p65SW982 cells

Identifiers

PMID37180904
PMCPMC10172753
OpenAlexW4367297838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.