Evidence map›Paper›PMID 37180829›Full record

ArticleChronic stress (Thousand Oaks, Calif.)

Unmet Social Needs and Patterns of Hair Cortisol Concentration in Mother-Child Dyads.

Victoria F Keeton, Julie T Bidwell, Euclides José de Mendonça Filho, Patricia P Silveira, Danielle Hessler, Matthew S Pantell, Holly Wing, Erika M Brown, Bradley Iott, Laura M Gottlieb

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chronic stress (Thousand Oaks, Calif.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Victoria F KeetonDepartment of Obstetrics, Gynecology, and the Reproductive Sciences, University of California, San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-6707-6611
Julie T BidwellUniversity of California, Davis, Betty Irene Moore School of Nursing, Sacramento, CA, USA.ORCID https://orcid.org/0000-0003-3995-7689
Euclides José de Mendonça FilhoDouglas Mental Health University Institute, Douglas Research Center, McGill University, Montreal, Quebec, Canada.
Patricia P SilveiraDouglas Mental Health University Institute, Douglas Research Center, McGill University, Montreal, Quebec, Canada.
Danielle HesslerDepartment of Family and Community Medicine, University of California, San Francisco, San Francisco, CA, USA.
Matthew S PantellDepartment of Pediatrics, University of California, San Francisco, San Francisco, CA, USA.
Holly WingUniversity of California, San Francisco, Center for Health and Community, San Francisco, CA, USA.
Erika M BrownCalifornia Policy Lab, University of California, Berkeley, CA, USA.
Bradley IottUniversity of California, San Francisco, Center for Health and Community, San Francisco, CA, USA.
Laura M GottliebDepartment of Family and Community Medicine, University of California, San Francisco, San Francisco, CA, USA.
University of California, San Francisco · USDouglas Mental Health University Institute · CAUC Davis Health · USUniversity of California, Berkeley · US

Funding

Transdisciplinary Research Training to Reduce Disparities in Preterm Birth and Improve Maternal and Neonatal OutcomesT32HD098057 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KUPPERMANN, MIRIAM · 2019 to 2023
$1.4M
NICHD NIH HHS T32 HD098057
6 · The paper itself

Abstract

Background: Mothers and their children demonstrate dyadic synchrony of hypothalamic-pituitary-adrenal (HPA) axis function, likely influenced by shared genetic or environmental factors. Although evidence has shown that chronic stress exposure has physiologic consequences for individuals-including on the HPA axis-minimal research has explored how unmet social needs such as food and housing instability may be associated with chronic stress and HPA axis synchrony in mother-child dyads. Methods: We conducted a secondary analysis of data from 364 mother-child dyads with low-income recruited during a randomized trial conducted in an urban pediatric clinic. We used latent profile analysis (LPA) to identify subgroups based on naturally occurring patterns of within-dyad hair cortisol concentration (HCC). A logistic regression model predicted dyadic HCC profile membership as a function of summative count of survey-reported unmet social needs, controlling for demographic and health covariates. Results: LPA of HCC data from dyads revealed a 2-profile model as the best fit. Comparisons of log HCC for mothers and children in each profile group resulted in significantly "higher dyadic HCC" versus "lower dyadic HCC" profiles (median log HCC for mothers: 4.64 vs 1.58; children: 5.92 vs 2.79, respectively; Conclusion: Mother-child dyads experience synchronous patterns of physiologic stress, and an increasing number of unmet social needs is associated with a profile of higher dyadic HCC. Interventions aimed at decreasing family-level unmet social needs or maternal stress are, therefore, likely to affect pediatric stress and related health inequities; efforts to address pediatric stress similarly may affect maternal stress and related health inequities. Future research should explore the measures and methods needed to understand the impact of unmet social needs and stress on family dyads.

Indexed as

hair cortisolmother–child dyadphysiologic stresssynchronyunmet social needs

Identifiers

PMID37180829
PMCPMC10170601
OpenAlexW4376642827

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.