Evidence map›Paper›PMID 37180808›Full record

ArticleFrontiers in cardiovascular medicine2023

Six-months clinical and intracoronary imaging follow-up after reverse T and protrusion or double-kissing and crush stenting for the treatment of complex left main bifurcation lesions.

Amr Ei Abouelnour, Maximilian Olschewski, Giulio Makmur, Helen Ullrich, Maike Knorr, Majid Ahoopai, Thomas Münzel, Tommaso Gori

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03714750 (Treatment of Coronary Bifurcation Lesions), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03714750 nacompletednot on this map

Treatment of Coronary Bifurcation Lesions: a Non-inferiority, Randomized, Controlled Procedural Outcomes Trial Comparing Reverse T and Protrusion Versus Double-kissing and Crush Stenting

TypeinterventionalSponsorTommaso GoriRan2018 to 2024Enrolled50ConditionsCoronary Artery DiseaseArmsDK crush, Reverse TAP
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Amr Ei AbouelnourUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Maximilian OlschewskiUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Giulio MakmurUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Helen UllrichUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Maike KnorrUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Majid AhoopaiUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Thomas MünzelUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Tommaso GoriUniversity Medical Center Mainz, Department of Cardiology, Mainz, Germany and German Center for Cardiac and Vascular Research (DZHK), Standort Rhein-Main, Germany.
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is a debate regarding the best stent strategy for unprotected distal left main (LM) bifurcation disease. Among two-stent techniques, double-kissing and crush (DKC) is favored in current guidelines but is complex and requires expertise. Reverse T and Protrusion (rTAP) was shown to be a comparable strategy regarding short-term efficacy and safety, but with reduced procedural complexity. Aim: To compare rTAP vs. DKC by optical coherence tomography (OCT) on the intermediate term. Methods: 52 consecutive patients with complex unprotected LM stenoses (Medina 0,1,1 or 1,1,1) were randomized to either DKC or rTAP and followed-up for a median of 189[180-263] days for clinical and OCT outcomes. Results: At follow-up OCT showed similar change in the side branch (SB) ostial area (primary endpoint). The confluence polygon showed a higher percentage of malapposed stent struts in the rTAP group that did not reach statistical significance (rTAP: 9.7[4.4-18.3] % vs. DKC: 3[0.07-10.9] %; Conclusion: At 6-months, OCT showed a similar change in the SB ostial area (primary endpoint) in rTAP compared to DKC. There was also a trend for smaller luminal areas in the confluence polygon and the distal parent vessel, and a larger neointimal area relative to the stent area, in DKC, along with a tendency for more malapposed stent struts in rTAP. Clinical Trial Registration: https://clinicaltrials.gov/ct2/show/NCT03714750, identifier: NCT03714750.

Indexed as

bifurcationdouble kissing and crushleft mainoptical coherence tomography (OCT)reverse t and protrusion

Identifiers

PMID37180808
PMCPMC10174439
OpenAlexW4367183795

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.