Evidence map›Paper›PMID 37180468›Full record

ArticleEuropean heart journal open2023

Left atrial appendage strain predicts subclinical atrial fibrillation in embolic strokes of undetermined source.

Jørg Saberniak, Loreta Skrebelyte-Strøm, Eivind Bjørkan Orstad, Janne Mykland Hilde, Magnar Gangås Solberg, Ole Morten Rønning, Harald Kjekshus, Kjetil Steine

Abstract read
In one paragraph

Article in European heart journal open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jørg SaberniakDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.ORCID https://orcid.org/0000-0002-9047-8467
Loreta Skrebelyte-StrømDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.ORCID https://orcid.org/0000-0002-0534-1694
Eivind Bjørkan OrstadDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.
Janne Mykland HildeDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.
Magnar Gangås SolbergFaculty of Medicine, University of Oslo, Oslo, Norway.
Ole Morten RønningDepartment of Neurology, Akershus University Hospital, Lørenskog, Norway.
Harald KjekshusDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.
Kjetil SteineDepartment of Cardiology, Division of Medicine, Akershus University Hospital, Sykehusveien 25, 1474 Nordbyhagen, PO box 1000, Lørenskog 1478, Norway.ORCID https://orcid.org/0000-0003-4265-3598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Left atrial (LA) strain is promising in prediction of clinical atrial fibrillation (AF) in stroke patients. However, prediction of subclinical AF is critical in patients with embolic strokes of undetermined source (ESUS). The aim of this prospective study was to investigate novel LA and left atrial appendage (LAA) strain markers in prediction of subclinical AF in ESUS patients. Methods and results: A total of 185 patients with ESUS, mean age 68 ± 13years, 33% female, without diagnosed AF, were included. LAA and LA function by conventional echocardiographic parameters and reservoir strain (Sr), conduit strain (Scd), contraction strain (Sct), and mechanical dispersion (MD) of Sr were assessed with transoesophageal and transthoracic echocardiography. Subclinical AF was detected by insertable cardiac monitors during follow-up. LAA strain was impaired in 60 (32%) patients with subclinical AF compared to those with sinus rhythm: LAA-Sr, 19.2 ± 4.5% vs. 25.6 ± 6.5% ( Conclusion: LAA function by strain and mechanical dispersion predicted subclinical AF in ESUS patients. These novel echocardiographic markers may improve risk stratification in ESUS patients.

Indexed as

Atrial strainCardiac embolismEmbolic stroke of undetermined sourceSubclinical atrial fibrillation

Identifiers

PMID37180468
PMCPMC10171229

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.