Evidence map›Paper›PMID 37180454›Full record

ArticleMicrosystems & nanoengineering2023

Enabling direct microcalorimetric measurement of metabolic activity and exothermic reactions onto microfluidic platforms via heat flux sensor integration.

Signe L K Vehusheia, Cosmin Roman, Olivier Braissant, Markus Arnoldini, Christofer Hierold

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Microsystems & nanoengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. High-throughput chip-calorimeter using a BiMicrosystems & nanoengineering · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Signe L K VehusheiaTannenstrasse 3, 8092 Zurich, Switzerland Micro and Nanosystems, Department of Mechanical and Process Engineering, ETH Zurich.
Cosmin RomanTannenstrasse 3, 8092 Zurich, Switzerland Micro and Nanosystems, Department of Mechanical and Process Engineering, ETH Zurich.
Olivier BraissantHegenheimermattweg 167C, 4123 Allschwil, Switzerland Center of Biomechanics and Biocalorimetry, Department of Biomedical Engineering, University of Basel.
Markus ArnoldiniOtto-Stern-Weg 3, 8093 Zurich, Switzerland Laboratory for Food Immunology, Department of Health Sciences and Technology, ETH Zurich.
Christofer HieroldTannenstrasse 3, 8092 Zurich, Switzerland Micro and Nanosystems, Department of Mechanical and Process Engineering, ETH Zurich.ORCID 0000-0002-1243-4039
ETH Zurich · CHUniversity of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

All biological processes use or produce heat. Traditional microcalorimeters have been utilized to study the metabolic heat output of living organisms and heat production of exothermic chemical processes. Current advances in microfabrication have made possible the miniaturization of commercial microcalorimeters, resulting in a few studies on the metabolic activity of cells at the microscale in microfluidic chips. Here we present a new, versatile, and robust microcalorimetric differential design based on the integration of heat flux sensors on top of microfluidic channels. We show the design, modeling, calibration, and experimental verification of this system by utilizing

Indexed as

BiosensorsMicrofluidicsSensors

Identifiers

PMID37180454
PMCPMC10169645
OpenAlexW4376643057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.