ReviewRSC advances2023
2-Oxindole and related heterocycles: synthetic methodologies for their natural products and related derivatives.
Review in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed.
- Culture conditions and microbial interactions shape VOC profiles and reveal 6-pentyl-α-pyrone and 2-oxindole as modulators of Colletotrichum gloeosporioides growth and pathogenicity.World journal of microbiology & biotechnology · 2026Article
- Magnesium-Assisted Photoinduced Polarity-Mismatched Coupling: Access to Thioester-Decorated Oxindoles and Fused Heterocycles.ChemSusChem · 2026Article
- Oxidative Rearrangement of Indoles Enabled by Promiscuous Cryptic Halogenation with Vanadium-Dependent Haloperoxidases.ACS catalysis · 2026Article
- Rongalite-mediated sequential homologative fluorination of oxindoles en route to 3-(fluoromethyl)-3-methylindolin-2-ones.RSC advances · 2026Article
- Chiral Monoamidines as Effective Organocatalysts for the Stereoselective Synthesis of Oxindoles under Homogeneous and Heterogeneous Conditions.The Journal of organic chemistry · 2025Article
- Transition-Metal-Based Dearomatization Strategy for the Synthesis of FunctionalizedOrganometallics · 2025Article
- A novel ene-reductase fromRSC advances · 2025Article
- Synthetic account on indoles and their analogues as potential anti-plasmodial agents.Molecular diversity · 2025Review
- Assessing Variability in Children's Exposure to Contaminants in Food: A Longitudinal Non-Targeted Analysis Study in Miami, Florida.Journal of xenobiotics · 2025Article
- Natural Products from Herbal Medicine Self-Assemble into Advanced Bioactive Materials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Article
- Heterocyclic-Based Analogues against Sarcine-Ricin Loop RNA fromMedicinal chemistry (Shariqah (United Arab Emirates)) · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural goods, medications, and pharmaceutically active substances all contain substituted oxindoles. Generally, the C-3 stereocenter of the substituents of oxindoles and their absolute arrangement have a substantial impact on the bioactivity of these substances. In this case, the desire for contemporary probe and drug-discovery programs for the synthesis of chiral compounds using desirable scaffolds with high structural diversity further drives research in this field. Also, the new synthetic techniques are generally simple to apply for the synthesis of other similar scaffolds. Herein, we review the distinct approaches for the synthesis of diverse useful oxindole scaffolds. Specifically, the research findings on the naturally existing 2-oxindole core and a variety of synthetic compounds having a 2-oxindole core are discussed. We present an overview of the construction of oxindole-based synthetic and natural products. In addition, the chemical reactivity of 2-oxindole and its related derivatives in the presence of chiral and achiral catalysts are thoroughly discussed. The data compiled herein provides broad information related to the bioactive product design, development, and applications of 2-oxindoles and the reported techniques will be helpful for the investigation of novel reactions in the future.
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Registered trials
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