Evidence map›Paper›PMID 37179648›Full record

ArticleACS omega2023

Structural and Functional Diversity in Rigid Thiosemicarbazones with Extended Aromatic Frameworks: Microwave-Assisted Synthesis and Structural Investigations.

Fernando Cortezon-Tamarit, Kexin Song, Navaratnarajah Kuganathan, Rory L Arrowsmith, Sara Raquel Mota Merelo de Aguiar, Philip A Waghorn, Adam Brookfield, Muralidharan Shanmugam, David Collison, Haobo Ge and 4 more

Abstract read
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In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Transmetalation in Cancer Pharmacology.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Fernando Cortezon-TamaritDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.ORCID https://orcid.org/0000-0002-2871-7965
Kexin SongDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Navaratnarajah KuganathanDepartment of Materials, Imperial College London, Royal School of Mines, Exhibition Road, London SW7 2AZ, U.K.ORCID https://orcid.org/0000-0002-4826-5329
Rory L ArrowsmithDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Sara Raquel Mota Merelo de AguiarDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Philip A WaghornDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, United Kingdom.
Adam BrookfieldDepartment of Chemistry, and Photon Science Institute, The University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Muralidharan ShanmugamDepartment of Chemistry, and Photon Science Institute, The University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.ORCID https://orcid.org/0000-0003-3818-1401
David CollisonDepartment of Chemistry, and Photon Science Institute, The University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom.
Haobo GeDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Gabriele Kociok-KöhnDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.ORCID https://orcid.org/0000-0002-7186-1399
Charareh PourzandDepartment of Life Sciences, University of Bath, Bath BA2 7AY, U.K.
Jonathan Robin DilworthDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.
Sofia Ioana PascuDepartment of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.ORCID https://orcid.org/0000-0001-6385-4650

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-standing interest in thiosemicarbazones (TSCs) has been largely driven by their potential toward theranostic applications including cellular imaging assays and multimodality imaging. We focus herein on the results of our new investigations into: (a) the structural chemistry of a family of rigid mono(thiosemicarbazone) ligands characterized by extended and aromatic backbones and (b) the formation of their corresponding thiosemicarbazonato Zn(II) and Cu(II) metal complexes. The synthesis of new ligands and their Zn(II) complexes was performed using a rapid, efficient and straightforward microwave-assisted method which superseded their preparation by conventional heating. We describe hereby new microwave irradiation protocols that are suitable for both imine bond formation reactions in the thiosemicabazone ligand synthesis and for Zn(II) metalation reactions. The new thiosemicarbazone ligands, denoted HL, mono(4-

Identifiers

PMID37179648
PMCPMC10173449

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.