Evidence map›Paper›PMID 37178987›Full record

ArticleMatrix biology : journal of the International Society for Matrix Biology2023

CaMKII inhibition due to TRIC-B loss-of-function dysregulates SMAD signaling in osteogenesis imperfecta.

Roberta Besio, Barbara M Contento, Nadia Garibaldi, Marta Filibian, Stephan Sonntag, Doron Shmerling, Francesca Tonelli, Marco Biggiogera, Marisa Brini, Andrea Salmaso and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Matrix biology : journal of the International Society for Matrix Biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Update on the Genetics of Osteogenesis Imperfecta.Calcified tissue international · 2024
    Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 4 countries.

Roberta BesioDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy.
Barbara M ContentoDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy.
Nadia GaribaldiDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy.
Marta FilibianCentro Grandi Strumenti, University of Pavia, Pavia, Italy; INFN, Istituto Nazionale di Fisica Nucleare-Pavia Unit, Pavia, Italy.
Stephan SonntagPolyGene AG, Rümlang, Switzerland; LIMES-Institute, University of Bonn, Bonn , Germany.
Doron ShmerlingPolyGene AG, Rümlang, Switzerland.
Francesca TonelliDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy.
Marco BiggiogeraDepartment of Biology and Biotechnology, University of Pavia, Pavia, Italy.
Marisa BriniDepartment of Biology, University of Padova, Padova, Italy; Centro Studi per la Neurodegenerazione (CESNE), University of Padova, Padova, Italy.
Andrea SalmasoDepartment of Biology, University of Padova, Padova, Italy.
Milena JovanovicSection on Heritable Disorders of Bone and Extracellular Matrix, Eunice Kennedy Shiver National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD, United States of America.
Joan C MariniSection on Heritable Disorders of Bone and Extracellular Matrix, Eunice Kennedy Shiver National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD, United States of America.
Antonio RossiDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy.
Antonella ForlinoDepartment of Molecular Medicine, Biochemistry Unit, University of Pavia, Pavia, Italy. Electronic address: aforlino@unipv.it.
University of Pavia · ITEunice Kennedy Shriver National Institute of Child Health and Human Development · USUniversity of Padua · ITPolyGene · CHUniversity of Bonn · DE

Funding

Heritable Disorders Of Connective TissueZIAHD000408 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MARINI, JOAN C · 2009 to 2023
$13.4M
Genetic Bone Disorders-Autosomal Recessive OIZ01HD008830 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI MARINI, JOAN C · 2007 to 2008
$982k
Intramural NIH HHS Z01 HD008830
6 · The paper itself

Abstract

Ca

Indexed as

Osteogenesis ImperfectaAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2CationsCollagenIon ChannelsMiceOsteoblastsOsteogenesisCalcium-Calmodulin-Dependent Protein Kinase Type 2CationsCollagenIon ChannelsTRIC-B protein, mouseBoneCollagenMurine modelOsteoblastOsteogenesis imperfectaTRIC-B

Identifiers

PMID37178987
PMCPMC11123566
OpenAlexW4376127447

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.