Evidence map›Paper›PMID 37178868›Full record

Observational studyIndian heart journal

Thrombolysis in STEMI in the era of COVID - Holding fort in cardiologist deficit locales.

Jnanaprakash B Karanth, Ananthakrishnan Ramamoorthy, Kiran Maribashetti, Ezhil Arasan Ramanan, Sailatha Ravi

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Tenecteplase vs Reteplase in Patients with Acute ST-Elevation Myocardial Infarction: A Retrospective Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Jnanaprakash B KaranthConsultant General Medicine, Shripad Hegde Kadave Institute of Medical Sciences, Sirsi -581402, India. Electronic address: jbkaranth@gmail.com.
Ananthakrishnan RamamoorthyDepartment of Cardiology, INHS Asvini, Colaba, Mumbai - 400005, India. Electronic address: anantha25@yahoo.com.
Kiran MaribashettiDepartment of Medicine, Command Hospital, Chandimandir, India. Electronic address: kmshetti.edu@gmail.com.
Ezhil Arasan RamananDr. VRE Research Laboratories, Chennai -600078, India. Electronic address: drpharmaindia@gmail.com.
Sailatha RaviDirector Pharmacogenomics, Dr. VRE Research Laboratories, Chennai -600078, India. Electronic address: drsr.prof@gmail.com.
Command Hospital · INDr. M.G.R. Educational and Research Institute · ININHS Asvini · INInstitute of Engineering · NPPharmacoGenetics (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the COVID-19 pandemic, the pharmaco-invasive approach in the management of ST Elevation Myocardial Infarction (STEMI) played a vital role in saving many lives. A retrospective observational study was conducted wherein 134 patients presenting with STEMI between (Dec 2019-Mar 2022) were thrombolysed with either streptokinase or tenecteplase in a centre where primary PCI was not available. There was no significant difference in the outcomes and their predictors between the SK and TNK groups. A prospective study with a larger sample size in the Indian population will be able to provide more substantial and promising results for further interventions.

Indexed as

CardiologistsCOVID-19Percutaneous Coronary InterventionST Elevation Myocardial InfarctionFibrinolytic AgentsHumansPandemicsProspective StudiesThrombolytic TherapyTissue Plasminogen ActivatorTreatment OutcomeFibrinolytic AgentsTissue Plasminogen ActivatorIschemic heart diseaseSTEMIThrombolysis

Identifiers

PMID37178868
PMCPMC10172153
OpenAlexW4376139507

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.