Evidence map›Paper›PMID 37178765›Full record

ArticleThe journal of allergy and clinical immunology. In practice2023

Patterns of Asthma Medication Use in New Zealand After Publication of National Asthma Guidelines.

Lee Hatter, Allie Eathorne, Tom Hills, Pepa Bruce, Claire Houghton, Mark Weatherall, Richard Beasley

Abstract read
PubMed Publisher
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Adoption and implementation of maintenance and reliever therapy for adults with moderate-to-severe asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  2. Patterns of asthma medication use and hospital discharges in New Zealand.The journal of allergy and clinical immunology. Global · 2024
    Article
  3. Can we measure whether asthma guidelines lead to improved care?NPJ primary care respiratory medicine · 2024
    Review
  4. Article
  5. The Role of ICS-Containing Rescue Therapy Versus SABA Alone in Asthma Management Today.The journal of allergy and clinical immunology. In practice · 2024
    Review
  6. Tracking the Trends in the Adoption of Reliever-Only ICS-Formoterol Therapy and SMART.The journal of allergy and clinical immunology. In practice · 2023
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lee HatterMedical Research Institute of New Zealand, Wellington, New Zealand; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
Allie EathorneMedical Research Institute of New Zealand, Wellington, New Zealand.
Tom HillsMedical Research Institute of New Zealand, Wellington, New Zealand.
Pepa BruceMedical Research Institute of New Zealand, Wellington, New Zealand.
Claire HoughtonMedical Research Institute of New Zealand, Wellington, New Zealand.
Mark WeatherallDepartment of Medicine, University of Otago Wellington, Wellington, New Zealand.
Richard BeasleyMedical Research Institute of New Zealand, Wellington, New Zealand; School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand. Electronic address: Richard.Beasley@mrinz.ac.nz.
Medical Research Institute of New Zealand · NZVictoria University of Wellington · NZUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn June 2020, the New Zealand (NZ) adolescent and adult asthma guidelines recommended budesonide/formoterol, taken as maintenance and/or reliever therapy, as the preferred therapeutic approach.

objectiveTo investigate whether these recommendations were associated with changes in clinical practice indicated by asthma medication use trends.

methodsNZ national dispensing data for inhaler medications from January 2010 to December 2021 were reviewed. Monthly "dispensings" of inhaled budesonide/formoterol, inhaled corticosteroid (ICS), other ICS/long-acting β

resultsBudesonide/formoterol dispensing increased markedly after July 1, 2020 (regression coefficient 41.1 inhalers dispensed/100,000 population per month [95% confidence interval (CI): 36.3-45.6, P < .0001]; 64.7% increase in the number of dispensings between July-December 2019 and July-December 2021), in contrast to "other ICS/LABA" (regression coefficient: -15.9 [95% CI: -22.2 to -9.6, P < .0001]; -1.7% decrease) and SABA (regression coefficient: -14.7 [95% CI: -29.7 to 0.3, P = .055]; -10.6% decrease), respectively.

conclusionIn NZ, a progressive increase in budesonide/formoterol dispensing, accompanied by a reduction in SABA and "other ICS/LABA" dispensing, occurred after publication of the 2020 NZ asthma guidelines. While acknowledging the limitations in the interpretation of temporal associations, these findings suggest that the transition to ICS/formoterol reliever-based therapy can be achieved if recommended and promoted as the preferred therapeutic approach in national guidelines.

Indexed as

Anti-Asthmatic AgentsAsthmaAdministration, InhalationAdolescentAdrenal Cortex HormonesAdultBudesonideBudesonide, Formoterol Fumarate Drug CombinationDrug CombinationsEthanolaminesFormoterol FumarateHumansNew ZealandAdrenal Cortex HormonesAnti-Asthmatic AgentsBudesonideBudesonide, Formoterol Fumarate Drug CombinationDrug CombinationsEthanolaminesFormoterol FumarateAsthmaDispensingGuidelinesICS/formoterolNew Zealand

Identifiers

PMID37178765
OpenAlexW4376127161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.