Evidence map›Paper›PMID 37178640›Full record

Trial reportDrug and alcohol dependence2023

Cognitive preoccupation with drinking and behavioral effects of alcohol as predictors of current consumption patterns.

Holley C Allen, Mark T Fillmore

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in Drug and alcohol dependence, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Holley C AllenDepartment of Psychology, University of Kentucky, USA.
Mark T FillmoreDepartment of Psychology, University of Kentucky, USA. Electronic address: fillmore@uky.edu.
University of Kentucky · US

Funding

Interdisciplinary Training in Alcohol ResearchT32AA027488 · NIAAA · UNIVERSITY OF KENTUCKY · PI Mark T Fillmore, Mark A Prendergast · 2019 to 2026
$2.0M
NIAAA NIH HHS T32 AA027488
6 · The paper itself

Abstract

backgroundAcute alcohol responses such as tolerance to alcohol-induced motor impairment and heightened sensitivity to alcohol-induced disinhibition are associated with heavier drinking. Additionally, certain cognitive characteristics may also indicate problem-drinking. For example, cognitive and emotional preoccupation (CEP) with alcohol is associated with heavier drinking. However, it is not clear if cognitive markers have value as predicators of heavier drinking beyond that of well-established alcohol response markers. The current study sought to test the predictive potential of CEP in the context of two well-documented alcohol response markers of heavy drinking.

methodsData aggregated from three studies comprised a sample of 94 young adult drinkers with no history of alcohol use disorder. Participants' motor coordination (grooved pegboard) and behavioral disinhibition (cued go/no-go) were assessed following consumption of 0.65g/kg alcohol and a placebo. CEP was measured via the Temptation and Restraint Inventory (TRI).

resultsDrinkers who expressed both alcohol response markers reported drinking higher doses regardless of their level of CEP. Among drinkers who expressed low sensitivity to both disinhibition and motor impairment, higher CEP was associated with higher typical quantities. Low sensitivity to motor impairment functioned as a standalone marker of heavier drinking.

conclusionsThe findings suggest that a combination of tolerance to motor impairment and high alcohol-induced disinhibition may be sufficient to promote heavier consumption even in the absence of cognitive markers associated with problem drinking. Results also suggest that cognitive characteristics may drive early drinking and contribute to the development of tolerance to acute alcohol effects.

Indexed as

AlcoholismEthanolAlcohol DrinkingCognitionCuesHumansYoung AdultEthanolAcute alcohol effectsAlcohol sensitivityAlcohol toleranceCognitive and emotional preoccupationDisinhibitionMarkers of alcohol-related problemsMotor impairment

Identifiers

PMID37178640
PMCPMC10330465
OpenAlexW4367042863

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.