Evidence map›Paper›PMID 37178430›Full record

ArticleAging clinical and experimental research2023

Multidimensional prognostic index predicts short- and long-term mortality and rehospitalizations in older patients with hip fracture.

Michela Zanetti, Paolo De Colle, Michele Niero, Gianluca Gortan Cappellari, Rocco Barazzoni, Chiara Ratti, Luigi Murena

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Article in Aging clinical and experimental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Pre-fracture functional status and 30-day recovery predict 5-year survival in patients with hip fracture: findings from a prospective real-world study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Observational
  5. Article
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5 · Who and what money

Authors and funding

7 authors.

Michela ZanettiDepartment of Medical Sciences, University of Trieste, Trieste, Italy. zanetti@units.it.
Paolo De ColleGeriatric Clinic, Maggiore Hospital, Azienda Sanitaria Universitaria Giuliano Isontina, Trieste, Italy.
Michele NieroDepartment of Medical Sciences, University of Trieste, Trieste, Italy.
Gianluca Gortan CappellariDepartment of Medical Sciences, University of Trieste, Trieste, Italy.
Rocco BarazzoniDepartment of Medical Sciences, University of Trieste, Trieste, Italy.
Chiara RattiDepartment of Medical Sciences, University of Trieste, Trieste, Italy.
Luigi MurenaDepartment of Medical Sciences, University of Trieste, Trieste, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultidimensional Prognostic Index (MPI), calculated on cognitive, functional, nutritional, social, pharmacological and comorbidity domains, strongly correlates with mortality in older patients. Hip fractures are a major health problem and are associated with adverse outcomes in those affected by frailty.

aimWe aimed at evaluating whether MPI is a predictor of mortality and rehospitalization in hip fracture older patients.

methodsWe investigated the associations of MPI with all-cause 3- and 6-month mortality and rehospitalization in 1259 older patients admitted for hip fracture surgical treatment and managed by an orthogeriatric team [age 85 years (65-109); male gender: 22%].

resultsOverall mortality was 11,4%, 17% and 23,5% at 3, 6 and 12 months from surgery (rehospitalizations: 15, 24,5 and 35,7%). MPI was associated (p < 0.001) with 3-, 6- and 12- month mortality and readmissions; Kaplan-Meier estimate for rehospitalization and survival according to MPI risk classes confirmed these results. In multiple regression analyses these associations were independent (p < 0.05) of mortality and rehospitalization-associated factors not included in the MPI, such as gender, age and post-surgical complications. Similar MPI predictive value was observed in patients undergoing endoprosthesis or other surgeries. ROC analysis confirmed that MPI was a predictor (p < 0.001) of both 3- and 6- month mortality and rehospitalization.

conclusionsIn hip fracture older patients, MPI is a strong predictor of 3-, 6- and 12- months mortality and rehospitalization, independently of surgical treatment and post-surgical complications. Therefore, MPI should be considered a valid pre-surgical tool to identify patients with higher clinical risk of adverse outcomes.

Indexed as

Hip FracturesPatient ReadmissionAgedAged, 80 and overComorbidityGeriatric AssessmentHospitalizationHumansMalePrognosisRisk FactorsFrailtyHip fractureMortalityMultidimensional Prognostic IndexRehospitalization

Identifiers

PMID37178430

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