ArticleClinical research in cardiology : official journal of the German Cardiac Society2024
A simply calculated nutritional index provides clinical implications in patients undergoing transcatheter aortic valve replacement.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 18 citations in OpenAlex.
- A novel nutritional index for hypertension risk and prediction: Cross-sectional, prospective, and trajectory evidence from the English Longitudinal Study of Ageing.The Journal of international medical research · 2026Article
- Association of triglyceride-cholesterol-body weight index with in-hospital mortality in critically ill patients with heart failure.Scientific reports · 2026Article
- Associations of cumulative exposure and dynamic trajectories of the triglyceride-total cholesterol-body weight index with new-onset cardiometabolic multimorbidity in middle-aged and older Chinese adults: evidence from a nationwide prospective cohort study.Cardiovascular diabetology · 2026Article
- Cross-Cultural Adaptation and Validation of the Simplified Diabetes Knowledge Test (Arabic Version) for Insulin-Dependent Diabetic Patients: A Cross-Sectional Study in Iraq.Journal of clinical medicine · 2026Article
- The Value of HALP Score in Predicting Adverse In-Hospital Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement.Diagnostics (Basel, Switzerland) · 2026Article
- Beyond HOMA-IR: Comparative Evaluation of Insulin Resistance and Anthropometric Indices Across Prediabetes and Type 2 Diabetes Mellitus in Metabolic Syndrome Patients.Life (Basel, Switzerland) · 2025Article
- Predictors of Length of Stay in Hospital After Transcatheter Aortic Valve Replacement: Impact of Naples Prognostic Score.Medicina (Kaunas, Lithuania) · 2025Article
- Prognostic value of nutritional changes in older patients following transcatheter aortic valve replacement.The journal of nutrition, health & aging · 2025Article
- Beyond traditional metrics: evaluating the triglyceride-total cholesterol-body weight index (TCBI) in cardiovascular risk assessment.BMC cardiovascular disorders · 2025Article
- Unraveling the role of cumulative triglyceride-total cholesterol-body weight index in stroke development: evidence from the CHARLS cohort.Frontiers in medicine · 2025Article
- Cardiac rehabilitation for TAVR patients: mechanisms, current status, and future directions.Frontiers in cardiovascular medicine · 2025Review
- The Triglycerides, total Cholesterol, and Body weight Index associating with frailty and predicting poor outcome after transcatheter aortic valve implantation: insights from LAPLACE-TAVI registry.European heart journal open · 2025Article
- Sex-Based Differences in the Associations Between Obesity- and Lipid-Related Indexes and Hyperuricemia Risk in Patients with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Association Between TCBI (Triglycerides, Total Cholesterol, and Body Weight Index) and Stroke-Associated Pneumonia in Acute Ischemic Stroke Patients.Clinical interventions in aging · 2024Article
- A Novel Score to Predict One-Year Mortality after Transcatheter Aortic Valve Replacement, Naples Prognostic Score.Medicina (Kaunas, Lithuania) · 2023Article
- A Nomogram for Predicting Coronary Artery Calcification Using Achilles Tendon Cross-Sectional Area, Mechanical Parameters, and TCBI.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundMalnutrition is associated with adverse outcomes in patients with aortic stenosis. The Triglycerides × Total Cholesterol × Body Weight Index (TCBI) is a simple scoring model to evaluate the status of nutrition. However, the prognostic relevance of this index in patients undergoing transcatheter aortic valve replacement (TAVR) is unknown. This study aimed to evaluate the association of the TCBI with clinical outcomes in patients undergoing TAVR.
methodsA total of 1377 patients undergoing TAVR were evaluated in this study. The TCBI was calculated by the formula; triglyceride (mg/dL) × total cholesterol (mg/dL) × body weight (kg)/1000. The primary outcome was all-cause mortality within 3 years.
resultsPatients with a low TCBI, based on a cut-off value of 985.3, were more likely to have elevated right atrial pressure (p = 0.04), elevated right ventricular pressure (p < 0.01), right ventricular systolic dysfunction (p < 0.01), tricuspid regurgitation ≥ moderate (p < 0.01). Patients with a low TCBI had a higher cumulative 3-year all-cause (42.3% vs. 31.6%, p < 0.01; adjusted HR 1.36, 95% CI 1.05-1.77, p = 0.02) and non-cardiovascular mortality (15.5% vs. 9.1%, p < 0.01; adjusted HR 1.95, 95% CI 1.22-3.13, p < 0.01) compared to those with a high TCBI. Adding a low TCBI to EuroSCORE II improved the predictive value for 3-year all-cause mortality (net reclassification improvement, 0.179, p < 0.01; integrated discrimination improvement, 0.005, p = 0.01).
conclusionPatients with a low TCBI were more likely to have right-sided heart overload and exhibited an increased risk of 3-year mortality. The TCBI may provide additional information for risk stratification in patients undergoing TAVR.
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