ArticleJACC. Cardiovascular imaging2023
Longitudinal Changes in Left Ventricular Diastolic Function in Late Life: The ARIC Study.
Article in JACC. Cardiovascular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Predictors of echocardiographic abnormalities in asymptomatic individuals with increased cardiothoracic ratio detected on chest radiography.American heart journal plus : cardiology research and practice · 2026Article
- Effect of Aficamten on Cardiac Structure and Function in Patients with Symptomatic Nonobstructive Hypertrophic Cardiomyopathy.Circulation · 2026Article
- Beyond Respiratory Support: Clinical Profiles and Factors Associated with Mortality in Heart Failure Patients Admitted to the ICU.Journal of clinical medicine · 2026Article
- Late-Life Echocardiographic Effects of the Amyloidogenic p.V142I Transthyretin Variant.Circulation. Heart failure · 2025Article
- Key Resting Echocardiographic Parameters for the Estimation of Exercise Parameters of Peak VO2, Heart Rate Recovery, and Ventilatory Efficiency.Journal of clinical medicine · 2025Article
- Article
- A biomarker framework for cardiac aging: the Aging Biomarker Consortium consensus statement.Life medicine · 2023Article
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundThere is limited data regarding longitudinal changes of diastolic function in the very old, who are at the highest risk for heart failure (HF).
objectivesThis study aims to quantify intraindividual longitudinal changes of diastolic function over 6 years in late life.
methodsThe authors studied 2,524 older adult participants in the prospective community-based ARIC (Atherosclerosis Risk In Communities) study who underwent protocol-based echocardiography at study visits 5 (2011-2013) and 7 (2018-2019). The primary diastolic measures were tissue Doppler e', E/e' ratio, and left atrial volume index (LAVI).
resultsMean age was 74 ± 4 years at visit 5 and 80 ± 4 at visit 7, 59% were women, and 24% were Black. At visit 5, mean e'
conclusionsDiastolic function generally deteriorates over 6.6 years in late life, particularly among persons with CV risk factors, and is associated with development of dyspnea. Further studies are necessary to determine if risk factor prevention or control will mitigate these changes.
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