Evidence map›Paper›PMID 37177877›Full record

ArticleClinical physiology and functional imaging2023

Adults with lower-limb amputation: Reduced multifidi muscle activity and extensor muscle endurance is associated with worse physical performance.

Jaclyn M Sions, Mayank Seth, Emma H Beisheim-Ryan, Gregory E Hicks, Ryan T Pohlig, John R Horne

Open access · bronzeAbstract read
In one paragraph

Article in Clinical physiology and functional imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jaclyn M SionsDepartment of Physical Therapy, Delaware Limb Loss Studies, University of Delaware, Newark, Delaware, USA.ORCID http://orcid.org/0000-0002-8151-1341
Mayank SethDepartment of Physical Therapy, Delaware Limb Loss Studies, University of Delaware, Newark, Delaware, USA.
Emma H Beisheim-RyanDepartment of Physical Therapy, Delaware Limb Loss Studies, University of Delaware, Newark, Delaware, USA.
Gregory E HicksDepartment of Physical Therapy, Delaware Limb Loss Studies, University of Delaware, Newark, Delaware, USA.
Ryan T PohligEpidemiology Program, STAR Campus, University of Delaware, Newark, Delaware, USA.
John R HorneIndependence Prosthetics-Orthotics, Inc., Newark, Delaware, USA.
University of Delaware · USNaval Medical Center San Diego · US

Funding

Predictive Modeling & Optimal Control Framework for Model-Based Epidemic Response in DelawareP20GM103446 · NIGMS · UNIVERSITY OF DELAWARE · PI MELINDA K DUNCAN · 2012 to 2026
$67.2M
PT/PHD Predoctoral Training Program Diversity SupplementT32HD007490 · NICHD · UNIVERSITY OF DELAWARE · PI DARCY S. REISMAN · 1996 to 2026
$3.7M
Trunk Muscle Characteristics and their Association with Balance, Function, and Participation among Individuals with AmputationsR03HD088668 · NICHD · UNIVERSITY OF DELAWARE · PI SIONS, JACLYN MEGAN · 2017 to 2018
$156k
FPTR Promotion of Doctoral Studies I and II scholarshipNICHD NIH HHS R03 HD088668NICHD NIH HHS T32 HD007490NIGMS NIH HHS 5P20GM103446NIGMS NIH HHS P20 GM103446
6 · The paper itself

Abstract

Trunk muscles may be an overlooked region of deficits following lower-limb amputation (LLA). This study sought to determine the extent that trunk muscle deficits are associated with physical function following amputation. Sedentary adults with a unilateral transtibial- (n = 25) or transfemoral-level (n = 14) amputation were recruited for this cross-sectional research study. Participants underwent a clinical examination that included ultrasound imaging of the lumbar multifidi muscles, the modified Biering-Sorensen Endurance Test (mBSET), and performance-based measures, that is, the Timed Up and Go (TUG), Berg Balance Scale (BBS), and 10-m Walk Test (10mWT). Associations between trunk muscle metrics and performance were explored with regression modeling, while considering covariates known to impact performance postamputation (p ≤ 0.100). Average ultrasound-obtained, lumbar multifidi activity was 14% and 16% for transfemoral- and transtibial-level amputations, respectively, while extensor endurance was 37.34 and 12.61 s, respectively. For TUG, nonamputated-side multifidi activity and an interaction term (level x non-amputated-side multifidi activity) explained 9.4% and 6.2% of the total variance, respectively. For 10mWT, beyond covariates, non-amputated-side multifidi activity and the interaction term explained 6.1% and 5.8% of the total variance, respectively. For TUG, extensor endurance and an interaction term (level x mBSET) explained 11.9% and 8.3% of the total variance beyond covariates; for BBS and 10mWT, extensor endurance explained 11.2% and 17.2% of the total variance, respectively. Findings highlight deficits in lumbar multifidi activity and extensor muscle endurance among sedentary adults with a LLA; reduced muscle activity and endurance may be important factors to target during rehabilitation to enhance mobility-related outcomes.

Indexed as

Amputation, SurgicalMuscle, SkeletalAdultCross-Sectional StudiesHumansPhysical Functional PerformanceWalk Testamputeesartificial limbslower extremityrecovery of functionrehabilitationultrasonographywalking speed

Identifiers

PMID37177877
PMCPMC10524971
OpenAlexW4376505064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.