Evidence map›Paper›PMID 37177782›Full record

ReviewBiophysical journal2023

GluD receptors are functional ion channels.

Janesh Kumar, Gabriela K Popescu, Stephanie C Gantz

Open access · greenAbstract readReview
In one paragraph

Review in Biophysical journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Molecular basis for ligand-gating of the human GluD1 receptor.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Glutamate Delta 1 Receptor in Synapses, Circuits, and Disease.The European journal of neuroscience · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Article
  10. An unexpected role for a glutamate receptor.Science (New York, N.Y.) · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Janesh KumarLaboratory of Membrane Protein Biology, Council of Scientific and Industrial Research (CSIR)-Centre for Cellular and Molecular Biology, Hyderabad, Telangana, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India.
Gabriela K PopescuDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University of Buffalo, SUNY, Buffalo, New York.
Stephanie C GantzDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Iowa Neuroscience Institute, University of Iowa, Iowa City, Iowa. Electronic address: stephanie-gantz@uiowa.edu.
Centre for Cellular and Molecular Biology · INJacobs Institute · USUniversity of Iowa · US

Funding

Experience-Dependent Reorganization of Excitatory Synapse ConnectivityR01MH118298 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PAN, JEN QIAN, POPESCU, GABRIELA K · 2019 to 2023
$3.3M
Molecular Physiology of NMDA ReceptorsR35NS132248 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Gabriela K Popescu · 2023 to 2026
$2.3M
Gating Mechanism of NMDA ReceptorsR01NS108750 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI POPESCU, GABRIELA K · 2019 to 2023
$1.5M
NIMH NIH HHS R01 MH118298NINDS NIH HHS R01 NS108750NINDS NIH HHS R35 NS132248Wellcome Trust
6 · The paper itself

Abstract

In this article, we review contemporary evidence that GluD receptors are functional ion channels whose depolarizing currents contribute to their biological functions, akin to all other members of the ionotropic glutamate receptor (iGluR) family.

Indexed as

Receptors, Ionotropic GlutamateReceptors, Ionotropic Glutamate

Identifiers

PMID37177782
PMCPMC10323023
OpenAlexW4376126424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.