Evidence map›Paper›PMID 37177252›Full record

ArticlePolymers2023

Antibacterial Composite Material Based on Polyhydroxybutyrate and Zn-Doped Brushite Cement.

Inna V Fadeeva, Dina V Deyneko, Alexander V Knotko, Anatoly A Olkhov, Pavel V Slukin, Galina A Davydova, Taisiia A Trubitsyna, Ilya I Preobrazhenskiy, Alevtina N Gosteva, Iulian V Antoniac and 1 more

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. [Preparation andZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 3 countries.

Inna V FadeevaA.A. Baikov Institute of Metallurgy and Material Science, Russian Academy of Sciences, Leninsky Prospect 49, 119334 Moscow, Russia.
Dina V DeynekoChemistry Department, Lomonosov Moscow State University, Vorobievy Gory 1, 119991 Moscow, Russia.ORCID 0000-0002-9422-1925
Alexander V KnotkoChemistry Department, Lomonosov Moscow State University, Vorobievy Gory 1, 119991 Moscow, Russia.
Anatoly A OlkhovN.N. Semenov Federal Research Center for Chemical Physics, Russian Academy of Sciences, Kosygina Street 4, Building 1, 119991 Moscow, Russia.ORCID 0000-0003-0615-6914
Pavel V SlukinState Scientific Center of Applied Microbiology and Biotechnology of Rospotrebnadzor 24, Block A, 142279 Obolensk, Russia.
Galina A DavydovaInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, 142290 Moscow, Russia.ORCID 0000-0003-4215-7084
Taisiia A TrubitsynaInstitute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, 142290 Moscow, Russia.ORCID 0000-0003-2304-8173
Ilya I PreobrazhenskiyMaterials Science Department, Lomonosov Moscow State University, Vorobievy Gory 1, 119991 Moscow, Russia.
Alevtina N GostevaKola Science Centre RAS, Tananaev Institute of Chemistry, Akademgorodok District 26A, 184209 Apatity, Russia.ORCID 0000-0002-8201-5876
Iulian V AntoniacFaculty of Materials Science and Engineering, University Politehnica of Bucharest, 313 Splaiul Independentei Street, District 6, 060042 Bucharest, Romania.ORCID 0000-0003-0112-3494
Julietta V RauIstituto di Struttura della Materia, Consiglio Nazionale delle Ricerche, ISM-CNR, Via del Fosso del Cavaliere 100, 00133 Rome, Italy.ORCID 0000-0002-7953-1853
Lomonosov Moscow State University · RUInstitute of Theoretical and Experimental Biophysics · RUAcademia Oamenilor de Știință din România · ROBaikov Institute of Metallurgy and Materials Science · RUInstitute of Structure of Matter · ITKola Science Centre · RUPlekhanov Russian University of Economics · RUState Research Center for Applied Microbiology and Biotechnology · RU

Funding

the Russian Science Foundation 22-23-00278the State Assignment 075-01025-23-00.the state of the Russian Federation 122011300125-2
6 · The paper itself

Abstract

A composite material based on electrospinning printed polyhydroxybutyrate fibers impregnated with brushite cement containing Zn substitution was developed for bone implant applications. Powder X-ray Diffraction (PXRD), Fourier Transform Infrared Spectroscopy and Scanning Electron Microscopy were applied for materials characterization. Soaking the composite in Ringer's solution led to the transformation of brushite into apatite phase, accompanied by the morphology changes of the material. The bending strength of the composite material was measured to be 3.1 ± 0.5 MPa. NCTC mouse fibroblast cells were used to demonstrate by means of the MTT test that the developed material was not cytotoxic. The behavior of the human dental pulp stem cells on the surface of the composite material investigated by the direct contact method was similar to the control. It was found that the developed Zn containing composite material possessed antibacterial properties, as testified by microbiology investigations against bacteria strains of

Indexed as

antibacterialcomposite materialpolyhydroxybutyrateZn-doped brushite cementZn-substituted brushite cement

Identifiers

PMID37177252
PMCPMC10181370
OpenAlexW4367315086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.