Evidence map›Paper›PMID 37177176›Full record

ReviewPolymers2023

Chitosan-Based Polymer Blends for Drug Delivery Systems.

Malkiet Kaur, Ameya Sharma, Vivek Puri, Geeta Aggarwal, Paramjot Maman, Kampanart Huanbutta, Manju Nagpal, Tanikan Sangnim

Abstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
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  5. Article
  6. Review
  7. Article
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  11. Review
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  13. Article
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  15. Review
  16. Chitosan Biomaterials: Advances and Challenges.International journal of molecular sciences · 2023
    Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Malkiet KaurChitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Ameya SharmaChitkara School of Pharmacy, Chitkara University, Himachal Pradesh 174103, India.
Vivek PuriChitkara School of Pharmacy, Chitkara University, Himachal Pradesh 174103, India.ORCID 0000-0002-4497-9412
Geeta AggarwalDepartment of Pharmaceutical Sciences, Delhi Pharmaceutical Sciences and Research University, New Delhi 110017, India.ORCID 0000-0003-3919-7018
Paramjot MamanParaxel International Pvt Ltd., Mohali 140308, India.
Kampanart HuanbuttaSchool of Pharmacy, Eastern Asia University, Pathum Thani 12110, Thailand.ORCID 0000-0001-8188-153X
Manju NagpalChitkara College of Pharmacy, Chitkara University, Punjab 140401, India.
Tanikan SangnimFaculty of Pharmaceutical Sciences, Burapha University, Chonburi 20131, Thailand.ORCID 0000-0002-9332-384X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polymers have been widely used for the development of drug delivery systems accommodating the regulated release of therapeutic agents in consistent doses over a long period, cyclic dosing, and the adjustable release of both hydrophobic and hydrophilic drugs. Nowadays, polymer blends are increasingly employed in drug development as they generate more promising results when compared to those of homopolymers. This review article describes the recent research efforts focusing on the utilization of chitosan blends with other polymers in an attempt to enhance the properties of chitosan. Furthermore, the various applications of chitosan blends in drug delivery are thoroughly discussed herein. The literature from the past ten years was collected using various search engines such as ScienceDirect, J-Gate, Google Scholar, PubMed, and research data were compiled according to the various novel carrier systems. Nanocarriers made from chitosan and chitosan derivatives have a positive surface charge, which allows for control of the rate, duration, and location of drug release in the body, and can increase the safety and efficacy of the delivery system. Recently developed nanocarriers using chitosan blends have been shown to be cost-effective, more efficacious, and prolonged release carriers that can be incorporated into suitable dosage forms.

Indexed as

biopolymerschitosandrug deliverynanocarrierspolymer blends

Identifiers

PMID37177176
PMCPMC10181148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.