Evidence map›Paper›PMID 37177014›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Viricidal Activity of Thermoplastic Polyurethane Materials with Silver Nanoparticles.

Rocío Díaz-Puertas, Enrique Rodríguez-Cañas, Melissa Bello-Perez, Marta Fernández-Oliver, Ricardo Mallavia, Alberto Falco

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rocío Díaz-PuertasInstitute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0002-3288-5697
Enrique Rodríguez-CañasInstitute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0002-7102-9711
Melissa Bello-PerezCentro Nacional de Biotecnología (CNB-CSIC), Departamento de Biología Molecular y Celular, Campus de la Universidad Autónoma de Madrid, c/Darwin 3, 20849 Madrid, Spain.ORCID 0000-0002-9212-083X
Marta Fernández-OliverInstitute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.
Ricardo MallaviaInstitute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0001-8058-1009
Alberto FalcoInstitute of Research, Development and Innovation in Healthcare Biotechnology of Elche (IDiBE), Miguel Hernández University (UMH), 03202 Elche, Spain.ORCID 0000-0001-7726-6577
Universitat de Miguel Hernández d'Elx · ESCentro Nacional de Biotecnología · ES

Funding

European Maritime, Fisheries and Aquaculture Fund (EMFAF) and Ministry of Agriculture, Fisheries and Food (MAPA) MetDisFishEuropean Regional Development Fund "Una forma de hacer Euro-pa" GVA-IDIFEDER_2018/020FEDER/Spanish Ministry of Science, Innovation and Universities - State Agency of Research RTI2018-101969-J-I00Spanish Ministerio de Economía y Competitividad PDI2021-123253OB-C21Spanish Ministry of Science and Innovation PTA2018-015394-I
6 · The paper itself

Abstract

The use of diverse Ag-based nanoparticulated forms has shown promising results in controlling viral propagation. In this study, a commercial nanomaterial consisting of ceramic-coated silver nanoparticles (AgNPs) was incorporated into thermoplastic polyurethane (TPU) plates using an industrial protocol, and the surface composition, ion-release dynamics and viricidal properties were studied. The surface characterization by FESEM-EDX revealed that the molar composition of the ceramic material was 5.5 P:3.3 Mg:Al and facilitated the identification of the embedded AgNPs (54.4 ± 24.9 nm). As determined by ICPMS, the release rates from the AgNP-TPU into aqueous solvents were 4 ppm/h for Ag and Al, and 28.4 ppm/h for Mg ions. Regarding the biological assays, the AgNP-TPU material did not induce significant cytotoxicity in the cell lines employed. Its viricidal activity was characterized, based on ISO 21702:2019, using the Spring viraemia of carp virus (SVCV), and then tested against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The results demonstrated that AgNP-TPU materials exhibited significant (75%) and direct antiviral activity against SVCV virions in a time- and temperature-dependent manner. Similar inhibition levels were found against SARS-CoV-2. These findings show the potential of AgNP-TPU-based materials as a supporting strategy to control viral spread.

Indexed as

3D nanomaterialsAg nanoparticlesceramicthermoplastic polyurethaneviricidal activity

Identifiers

PMID37177014
PMCPMC10180066
OpenAlexW4367052898

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.