Evidence map›Paper›PMID 37176994›Full record

ReviewNanomaterials (Basel, Switzerland)2023

Tissue-Engineered Nanomaterials Play Diverse Roles in Bone Injury Repair.

Teng Wan, Meng Zhang, Hao-Ran Jiang, Yi-Chong Zhang, Xiao-Meng Zhang, Yi-Lin Wang, Pei-Xun Zhang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teng WanDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0002-0474-6534
Meng ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Hao-Ran JiangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Yi-Chong ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Xiao-Meng ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.
Yi-Lin WangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0003-3930-2260
Pei-Xun ZhangDepartment of Orthopedics and Trauma, Peking University People's Hospital, Beijing 100044, China.

Funding

Cross-cooperation project of Beijing Science and Technology New Star Program 20220484233
6 · The paper itself

Abstract

Nanomaterials with bone-mimicking characteristics and easily internalized by the cell could create suitable microenvironments in which to regulate the therapeutic effects of bone regeneration. This review provides an overview of the current state-of-the-art research in developing and using nanomaterials for better bone injury repair. First, an overview of the hierarchical architecture from the macroscale to the nanoscale of natural bone is presented, as these bone tissue microstructures and compositions are the basis for constructing bone substitutes. Next, urgent clinical issues associated with bone injury that require resolution and the potential of nanomaterials to overcome them are discussed. Finally, nanomaterials are classified as inorganic or organic based on their chemical properties. Their basic characteristics and the results of related bone engineering studies are described. This review describes theoretical and technical bases for the development of innovative methods for repairing damaged bone and should inspire therapeutic strategies with potential for clinical applications.

Indexed as

bone tissue injurydrug loadingengineered bone tissuenanomaterialnanoparticletargeted therapy

Identifiers

PMID37176994
PMCPMC10180507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.