Evidence map›Paper›PMID 37176770›Full record

ArticleJournal of clinical medicine2023

Value of Fractional Exhaled Nitric Oxide in Diagnosing Mild Asthma Responsive to Inhaled Corticosteroids.

Natasa Karamarkovic Lazarusic, Eugenija Kasap Basioli, Ena Tolic, Martina Dokoza, Gordana Pavlisa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natasa Karamarkovic LazarusicOutpatient Centre for Respiratory Diseases, 10000 Zagreb, Croatia.
Eugenija Kasap BasioliDepartment of Pulmonology, General Hospital, 23000 Zadar, Croatia.
Ena TolicClinic for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.
Martina DokozaDepartment of Pulmonology, General Hospital, 23000 Zadar, Croatia.ORCID 0009-0003-3976-4665
Gordana PavlisaClinic for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-7162-7212
University Hospital Centre Zagreb · HRUniversity of Zadar · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMild asthma is often characterized by normal spirometric values and a negative bronchodilation test (BDT), which makes accurate diagnosis challenging. The aim of our study was to evaluate the diagnostic accuracy of fractional exhaled nitric oxide (FeNO) in mild asthma.

methodsIn adults with symptoms suggestive of asthma and normal spirometry values, BDT, FeNO, BPT and skin prick testing were performed. Patients with positive BPT started inhaled corticosteroid (ICS) therapy. Those with positive response to ICS were considered asthmatics.

resultsThere were 142 asthmatics and 140 non-asthmatics. No significant difference was found in BDT between the groups,

conclusionsFeNO has insufficient sensitivity and specificity in mild asthma and the application of BPT is often necessary to establish an accurate diagnosis.

Indexed as

diagnostic accuracyfractional exhaled nitric oxidemethacholine provocation testmild asthmasensitivityspecificity

Identifiers

PMID37176770
PMCPMC10179178
OpenAlexW4376630627

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.