ArticleJournal of clinical medicine2023
Association between Low Forced Vital Capacity and High Pneumonia Mortality, and Impact of Muscle Power.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Integrating Leg-Press Strength and Nutritional Status Improves 16-Year Mortality Risk Stratification in General Older Adults.Journal of cachexia, sarcopenia and muscle · 2026Article
- Combining Geriatric Nutritional Risk Index with Total Cholesterol to Predict Pneumonia Mortality Risks in a Cohort of General Older Adults.Nutrients · 2026Article
- Observational
- Ultrasonographic assessment of thenar muscles for diagnosing sarcopenic obesity in patients with schizophrenia.Frontiers in psychiatry · 2025Article
- Nrf2 Deficiency Exacerbates the Decline in Swallowing and Respiratory Muscle Mass and Function in Mice with Aspiration Pneumonia.International journal of molecular sciences · 2024Article
- Importance of Skeletal Muscle and Interdisciplinary Team Approach in Managing Pneumonia in Older People.Journal of clinical medicine · 2023Article
- Impacts of body positions on the geniohyoid muscle contraction and swallowing difficulty in healthy adults.Clinical and experimental dental research · 2023Article
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Authors and funding
9 authors.
Funding
Abstract
Impaired % predicted value forced vital capacity (% FVC) is related to higher all-cause mortality in aged adults, and strong muscle force may improve this relationship. A muscle disease, sarcopenia, causes higher mortality. We aimed to identify the unknown disease that relates impaired % FVC with higher mortality in aged adults among the three major leading causes of death, and the effect of strong leg force on this relationship. Cox proportional hazard model analyzed the longitudinal Tsurugaya cohort that registered 1048 aged Japanese for 11 years. The primary outcome was the relationship between % FVC and mortality by cancer, cardiovascular disease, or pneumonia. Exposure variables were % FVC or leg force divided by 80% or median values, respectively. The secondary outcome was the effects of leg force on the relationship. Among the diseases, % FVC < 80% was related only to higher pneumonia mortality (hazard ratio [HR], 4.09; 95% CI, 1.90-8.83) relative to the % FVC ≥ 80% group before adjustment. Adding the leg force as an explanatory variable reduced the HR to 3.34 (1.54-7.25). Weak leg force might indicate sarcopenia, and its prevention may improve higher pneumonia mortality risk related to impaired % FVC, which we may advise people in clinical settings.
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