ArticleJournal of clinical medicine2023
The Association between Autoimmune Thyroid Disease and Ocular Surface Damage: A Retrospective Population-Based Cohort Study.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Approach to the patient: therapeutic mitigation of lacrimal manifestations in thyroid eye disease.The Journal of clinical endocrinology and metabolism · 2026Review
- Peripheral Hypertrophic Subepithelial Corneal Degeneration.Journal of clinical medicine · 2026Article
- The Relationship Between Composite Inflammatory Indices and Dry Eye in Hashimoto's Disease-Induced Hypothyroid Patients.Biomedicines · 2025Article
- Sleep quality and its determinants in patients with thyroid eye disease: a cross-sectional study.European journal of medical research · 2025Article
- Clinical characteristics of dry eye patients with thyroid disorders: a cross-sectional study.BMC ophthalmology · 2025Article
- Predictive modeling of graves' orbitopathy activity based on meibomian glands analysis using in vivo confocal microscopy.BMC endocrine disorders · 2025Article
- Research progress on the immune mechanism of thyroid-related eye disease combined with dry eye.Journal of ophthalmic inflammation and infection · 2025Article
- Hashimoto's Thyroiditis and Dry Eye Disease.Journal of clinical medicine · 2025Article
- Advances of IGF-1R inhibitors in Graves' ophthalmopathy.International ophthalmology · 2024Review
- Inflammatory bowel disease and the associated risk of dry eye and ocular surface injury: a nationwide matched cohort study.BMC ophthalmology · 2023Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Autoimmune thyroid diseases (ATDs) are potentially connected to lacrimal gland dysfunction and ocular surface disruption. This study aimed to evaluate the relationships between ATD, dry eye disease (DED), and corneal surface damage. In a matched nationwide cohort study, we used Taiwan's National Health Insurance research database to compare the incidences of DED and corneal surface damage between subjects with and without ATD. Multivariable Cox proportional hazards regression models were used to estimate the adjusted hazard ratio (aHR) and 95% confidence interval (CI) for the ophthalmological outcomes. A total of 50,251 matched pairs with 748,961 person-years of follow-up were included for analysis. The incidence of DED was 16.37 and 8.36 per 1000 person-years in the ATD and non-ATD groups, respectively. ATDs were significantly associated with increased DED (aHR: 1.81, 95% CI: 1.73-1.89,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.