Evidence map›Paper›PMID 37176623›Full record

ArticleJournal of clinical medicine2023

Handgrip Strength and Muscle Quality: Results from the National Health and Nutrition Examination Survey Database.

Zhangxin Wen, Jiaxuan Gu, Rong Chen, Qinyi Wang, Na Ding, Lingqiong Meng, Xiangbing Wang, Hong Liu, Zhifeng Sheng, Houfeng Zheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Zhangxin WenDepartment of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, China.
Jiaxuan GuDiseases & Population (DaP) Geninfo Lab, School of Lifesciences, Westlake University, 600 Dunyu Road, Hangzhou 310030, China.
Rong ChenKey Laboratory of Endocrinology, Department of Endocrinology, National Health and Family Planning Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Shuaifuyuan No. 1, Beijing 100730, China.
Qinyi WangNational Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, Health Management Center, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, Changsha 410011, China.
Na DingDepartment of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, China.
Lingqiong MengDepartment of Nutritional Sciences, Rutgers University, New Brunswick, NJ 08901, USA.
Xiangbing WangDivisions of Endocrinology, Metabolism and Nutrition, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.ORCID 0000-0002-8242-7475
Hong LiuDepartment of Metabolism and Endocrinology, Zhuzhou Hospital of Xiangya School of Medicine, Central South University, 116 Changjiang South Road, Zhuzhou 412007, China.
Zhifeng ShengNational Clinical Research Center for Metabolic Diseases, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, Department of Metabolism and Endocrinology, Health Management Center, The Second Xiangya Hospital of Central South University, 139 Middle Renmin Road, Changsha 410011, China.ORCID 0000-0003-2308-3024
Houfeng ZhengDiseases & Population (DaP) Geninfo Lab, School of Lifesciences, Westlake University, 600 Dunyu Road, Hangzhou 310030, China.
Central South University · CNRutgers, The State University of New Jersey · USWestlake University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Bethune Charitable Foundation G-X-2019-1107-3Changsha Nature Science Foundation kq2014251Hunan Nature Science Foundation 2018JJ2574Hunan Nature Science Foundation 2022JJ70172National Nature Science Foundation of China 81870622]
6 · The paper itself

Abstract

backgroundHandgrip strength (HGS) and the appendicular lean mass index (ALMI) are important determinants of sarcopenia. Muscle quality (MQ) is a measure of muscle strength relative to muscle mass. We examined trends in handgrip strength, the appendicular lean mass index, and analyzed their relationship with age, anthropometry, and body composition in a sample of participants in the United States (US).

methodsThis cross-sectional study analyzed data from 14,741 US males (49.7%) and females (50.3%) 6-80 years old who responded to the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2014. Dual X-ray absorptiometry was used to measure appendicular skeletal muscle mass. HGS was evaluated using the Takei Digital Grip Strength Dynamometer. Smoothed normative curves for HGS and the ALMI were constructed using a generalized additive model. Multiple regression analyses were used to examine associations of HGS and the ALMI with age, nutrition-related factors, physical activity, and body composition.

resultsMean HGS and the ALMI declined with advancing age. While mean HGS increased with the ALMI, it decreased with the fat mass index. HGS increased in males with an increase in body mass index, energy intake, the ALMI, and vitamins; however, HGS in females increased with albumin, but it had a negative association with the fat mass index and age, but not with increasing adiposity.

conclusionsHGS and the ALMI change with age: HGS increases with age, then stabilizes and declines; the ALMI increases with age, then stabilizes. In addition, we provide evidence for the effect of anthropometry, nutrition, physical activity, and body composition on HGS and the ALMI in US population.

Indexed as

ageappendicular lean mass indexhandgrip strengthphysical activitysarcopenia

Identifiers

PMID37176623
PMCPMC10179381
OpenAlexW4367311189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.