ArticleJournal of clinical medicine2023
Patterns of Cognitive Impairment in Hemodialysis Patients and Related Factors including Depression and Anxiety.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 16 citations in OpenAlex.
- Enhanced cognitive outcomes with triple-mode dialysis in kidney failure: role of protein-bound toxin clearance.Renal failure · 2025Trial
- Serum BDNF and cognitive risk in maintenance hemodialysis: a machine learning study.Renal failure · 2026Article
- Neuro-Renal Crosstalk Across the Chronic Kidney Disease Spectrum: Stage-Dependent Molecular Mechanisms of Cognitive Impairment-An Integrative Review.International journal of molecular sciences · 2026Review
- Cognitive Performance After Kidney and Liver Transplantation: A Cross-Sectional Study Using Addenbrooke's Cognitive Examination III.Journal of clinical medicine · 2026Article
- Serum Creatinine Clearance and Cognitive Function in Older Adults: Mediating Effects of Systemic Inflammatory Response Index.Brain and behavior · 2026Article
- Longitudinal Changes in Depression, Anxiety and Stress Symptoms Among Hemodialysis Patients.Clinics and practice · 2026Article
- Association between protein-energy wasting and cognitive impairment in maintenance hemodialysis patients.Frontiers in nutrition · 2026Article
- Correlation between symptom distress and quality of life in patients with Chronic Kidney Disease Stage 5 undergoing hemodialysis in China: a multi-center cross-sectional study.Frontiers in psychiatry · 2026Article
- Sex-related disparities in cognitive impairment in kidney transplant patients with kidney failure.Journal of nephrology · 2025Article
- Article
- The Diagnostic Performance of Screening Instruments for Mild Cognitive Impairment and Dementia in Chronic Kidney Disease and Kidney Failure: A Systematic Review and Meta-analysis.Kidney medicine · 2025Article
- Prevalence and Pattern of Cognitive Impairment in Patients on Maintenance Hemodialysis.Cureus · 2025Article
- Cognitive impairment in kidney transplanted patients.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Cognitive Performance in Patients With Alcohol-Associated Liver Disease Undergoing Liver Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- The mediating effect of alexithymia in the symptom burden and depression in patients with maintenance hemodialysis.Frontiers in psychology · 2025Article
- The Clock Drawing Task reveals executive dysfunction in the dialysis population - an underrecognized and underestimated problem.Renal failure · 2024Article
- Sedentary Lifestyle Is a Modifiable Risk Factor for Cognitive Impairment in Patients on Dialysis and after Kidney Transplantation.Journal of clinical medicine · 2024Article
- Cognitive impairment in patients awaiting kidney and liver transplantation-A clinically relevant problem?Brain and behavior · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHemodialysis patients are at higher risk of developing cognitive impairment, but the pattern of affected cognitive domains is still undetermined. Little is also known about the symptoms of depression and anxiety in hemodialysis patients.
methodsIn this cross-sectional study, we included 74 consecutive adult patients undergoing hemodialysis. Cognitive functions were assessed using the Addenbrooke Cognitive Test III. In addition, all patients were screened for symptoms of depression and anxiety using the Hospital Anxiety and Depression Scale.
resultsThe mean age of hemodialysis patients was 65.69 ± 14 years. Among the patients, there were 27% and 31% of patients with mild cognitive impairment and suspected dementia, respectively. In the group of patients with suspected dementia, all cognitive functions had significantly lower values compared to these functions in incognitively unimpaired and mild cognitive impairment patients. The most impaired domain was verbal fluency, which reflects impairments in executive function. Depression and anxiety symptoms were observed in 28% and 22% of patients, respectively. Patients with anxiety symptoms had higher levels of endogenous creatinine, parathyroid hormone, and hemoglobin, as well as decreased creatinine clearance, being younger and less educated. No factors contributing to the occurrence of depressive symptoms were found.
conclusionCognitive dysfunction is a significant problem in hemodialysis patients. Our study showed that the prevalence of cognitive impairment and depression and anxiety symptoms in hemodialysis patients was high. The domain of executive functions was most affected. Furthermore, creatinine, parathyroid hormone, hemoglobin levels, creatinine clearance, and education affected the anxiety scale score.
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