Evidence map›Paper›PMID 37176543›Full record

ArticleJournal of clinical medicine2023

Scleral Thickness as a Risk Factor for Central Serous Chorioretinopathy and Pachychoroid Neovasculopathy.

Leonie F Keidel, Benedikt Schworm, Julian Langer, Nikolaus Luft, Tina Herold, Felix Hagenau, Julian E Klaas, Siegfried G Priglinger, Jakob Siedlecki

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Imaging in Pachychoroid DiseaseTurkish journal of ophthalmology · 2025
    Review
  6. Article
  7. Article
  8. Spotlight on Lattice Degeneration Imaging Techniques.Clinical ophthalmology (Auckland, N.Z.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Leonie F KeidelDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Benedikt SchwormDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.ORCID 0000-0003-0753-2408
Julian LangerDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Nikolaus LuftDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Tina HeroldDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Felix HagenauDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.ORCID 0000-0002-1322-0649
Julian E KlaasDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Siegfried G PriglingerDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.ORCID 0000-0002-5580-612X
Jakob SiedleckiDepartment of Ophthalmology, Ludwig-Maximilians-University, 80336 Munich, Germany.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the pathophysiology of central serous chorioretinopathy (CSC), scleral changes inducing increased venous outflow resistance are hypothesized to be involved. This work aims to investigate anterior scleral thickness (AST) as a risk factor for pachychoroid disorders. A randomized prospective case-control study was performed at the Ludwig Maximilians University, Department of Ophthalmology. In patients with CSC or pachychoroid neovasculopathy (PNV) and in an age- and refraction-matched control group, swept source optical coherence tomography (SS-OCT) was used to measure anterior scleral thickness (AST). Subfoveal choroidal thickness (SFCT) was assessed using enhanced depth imaging OCT (EDI-OCT). In total, 46 eyes of 46 patients were included in this study, with 23 eyes in the CSC/PNV and 23 eyes in the control group. A significantly higher AST was found in the CSC/PNV compared with the control group (403.5 ± 68.6 (278 to 619) vs. 362.5 ± 62.6 (218 to 498) µm;

Indexed as

anterior scleral thicknesscentral serous chorioretinopathypachychoroidpachychoroid neovascularisationpachyscleraswept-source optical coherence tomography

Identifiers

PMID37176543
PMCPMC10179194
OpenAlexW4366988288

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.